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TLR9 — TRAF3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Häcker et al., Nat Rev Immunol 2011
:
In this Review, we discuss our current understanding of the
role of
TRAF3 in TNFR and
TLR signalling pathways, and its role in disease
Clark et al., Proc Natl Acad Sci U S A 2011
:
Toll-like receptor ( TLR ) ligands that signal via TIR-domain containing adapter inducing IFNß ( TRIF )
activate the I?B kinase ( IKK ) -related kinases,
TRAF associated NF?B activator ( TANK) binding kinase-1 (TBK1 ) and IKKe, which then phosphorylate IRF3 and induce the production of IFNß