Gene interactions and pathways from curated databases and text-mining

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ARF1 — EPHB2

Text-mined interactions from Literome

Lachat et al., Oncogene 2004 (Glioma) : INK4a/Arf is required for suppression of EGFR/DeltaEGFR ( 2-7 ) -dependent ERK activation in mouse astrocytes and glioma
Tushir et al., EMBO J 2007 : Second, ARF6 induced ERK activation regulates Rac1 activation during tubule initiation through the expression of the receptor for urokinase type plasminogen activator
Dong et al., J Biol Chem 2011 : Interestingly, mutation of the double Trp motif and siRNA mediated depletion of ARF1 attenuate a ( 2B ) -AR mediated activation of extracellular signal regulated kinases 1/2 ( ERK1/2 ) without altering receptor intracellular trafficking, whereas expression of the constitutively active mutant ARF1Q71L and ARNO, a GDP-GTP exchange factor of ARF1, markedly enhances the activation of Raf1, MEK1, and ERK1/2