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ARF1 — EPHB2
Text-mined interactions from Literome
Lachat et al., Oncogene 2004
(Glioma) :
INK4a/Arf is
required for suppression of EGFR/DeltaEGFR ( 2-7 ) -dependent
ERK activation in mouse astrocytes and glioma
Tushir et al., EMBO J 2007
:
Second,
ARF6 induced
ERK activation regulates Rac1 activation during tubule initiation through the expression of the receptor for urokinase type plasminogen activator
Dong et al., J Biol Chem 2011
:
Interestingly, mutation of the double Trp motif and siRNA mediated depletion of ARF1 attenuate a ( 2B ) -AR mediated activation of extracellular signal regulated kinases 1/2 ( ERK1/2 ) without altering receptor intracellular trafficking, whereas expression of the constitutively active mutant
ARF1Q71L and ARNO, a GDP-GTP exchange factor of ARF1, markedly
enhances the activation of Raf1, MEK1, and
ERK1/2