Gene interactions and pathways from curated databases and text-mining

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PI3 — SEC61B

Text-mined interactions from Literome

Astoul et al., J Cell Biol 1999 : Membrane translocation of PKB and subsequent PKB activation are dependent on BCR activation of phosphatidylinositol 3-kinase (PI3K)
Marshall et al., J Exp Med 2000 : Membrane recruitment requires phosphatidylinositol 3-kinase (PI3K) activity and an intact PI ( 3,4, 5 ) P ( 3 ) -binding motif, suggesting that membrane association occurs through binding to 3-phosphoinositides
Papadopoulou et al., Molecular cancer 2008 (Prostatic Neoplasms) : Membrane androgen receptor activation triggers down-regulation of PI-3K/Akt/NF-kappaB activity and induces apoptotic responses via Bad, FasL and caspase-3 in DU145 prostate cancer cells