Gene interactions and pathways from curated databases and text-mining

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DKK1 — MYC

Text-mined interactions from Literome

Cowling et al., Mol Cell Biol 2007 (Breast Neoplasms...) : Myc dependent repression of DKK1 and SFRP1 is accompanied by Wnt target gene activation and endogenous T-cell factor activity
Cho et al., J Biol Chem 2013 (Breast Neoplasms...) : BMI1 mediated repression of DKK proteins ; in particular, DKK1 led to up-regulation of WNT target c-Myc , which in turn further led to transcriptional autoactivation of BMI1