Sample Summary Tracks
 
Sample Summary tracks

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Adipose Derived Mesenchymal Stem Cell Cultured Cells Summary  Roadmap Epigenome Adipose Derived Mesenchymal Stem Cell Cultured Cells Summary for 7 assay type(s)  
Adipose Nuclei Summary  Roadmap Epigenome Adipose Nuclei Summary for 8 assay type(s)  
Adipose Tissue Summary  Roadmap Epigenome Adipose Tissue Summary for 4 assay type(s)  
Adrenal Gland Summary  Roadmap Epigenome Adrenal Gland Summary for 7 assay type(s)  
Adult Kidney Summary  Roadmap Epigenome Adult Kidney Summary for 8 assay type(s)  
Adult Liver Summary  Roadmap Epigenome Adult Liver Summary for 10 assay type(s)  
Aorta Summary  Roadmap Epigenome Aorta Summary for 8 assay type(s)  
Bladder Summary  Roadmap Epigenome Bladder Summary for 5 assay type(s)  
Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Summary  Roadmap Epigenome Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Summary for 9 assay type(s)  
Brain Angular Gyrus Summary  Roadmap Epigenome Brain Angular Gyrus Summary for 9 assay type(s)  
Brain Anterior Caudate Summary  Roadmap Epigenome Brain Anterior Caudate Summary for 9 assay type(s)  
Brain Cerebellum Summary  Roadmap Epigenome Brain Cerebellum Summary for 1 assay type(s)  
Brain Cingulate Gyrus Summary  Roadmap Epigenome Brain Cingulate Gyrus Summary for 9 assay type(s)  
Brain Germinal Matrix Summary  Roadmap Epigenome Brain Germinal Matrix Summary for 10 assay type(s)  
Brain Hippocampus Middle Summary  Roadmap Epigenome Brain Hippocampus Middle Summary for 10 assay type(s)  
Brain Inferior Temporal Lobe Summary  Roadmap Epigenome Brain Inferior Temporal Lobe Summary for 9 assay type(s)  
Brain Mid Frontal Lobe Summary  Roadmap Epigenome Brain Mid Frontal Lobe Summary for 9 assay type(s)  
Brain Substantia Nigra Summary  Roadmap Epigenome Brain Substantia Nigra Summary for 9 assay type(s)  
Breast Fibroblast Primary Cells Summary  Roadmap Epigenome Breast Fibroblast Primary Cells Summary for 7 assay type(s)  
Breast Luminal Epithelial Cells Summary  Roadmap Epigenome Breast Luminal Epithelial Cells Summary for 10 assay type(s)  
Breast Myoepithelial Cells Summary  Roadmap Epigenome Breast Myoepithelial Cells Summary for 12 assay type(s)  
Breast Stem Cells Summary  Roadmap Epigenome Breast Stem Cells Summary for 5 assay type(s)  
Breast vHMEC Summary  Roadmap Epigenome Breast vHMEC Summary for 12 assay type(s)  
CD14 Primary Cells Summary  Roadmap Epigenome CD14 Primary Cells Summary for 8 assay type(s)  
CD15 Primary Cells Summary  Roadmap Epigenome CD15 Primary Cells Summary for 7 assay type(s)  
CD19 Primary Cells Summary  Roadmap Epigenome CD19 Primary Cells Summary for 9 assay type(s)  
CD20 Primary Cells Summary  Roadmap Epigenome CD20 Primary Cells Summary for 1 assay type(s)  
CD3 Primary Cells Summary  Roadmap Epigenome CD3 Primary Cells Summary for 10 assay type(s)  
CD34 Cultured Cells Summary  Roadmap Epigenome CD34 Cultured Cells Summary for 6 assay type(s)  
CD34 Primary Cells Summary  Roadmap Epigenome CD34 Primary Cells Summary for 7 assay type(s)  
CD4 Memory Primary Cells Summary  Roadmap Epigenome CD4 Memory Primary Cells Summary for 11 assay type(s)  
CD4 Naive Primary Cells Summary  Roadmap Epigenome CD4 Naive Primary Cells Summary for 11 assay type(s)  
CD4 Primary Cells Summary  Roadmap Epigenome CD4 Primary Cells Summary for 5 assay type(s)  
CD4+ CD25+ CD127- Treg Primary Cells Summary  Roadmap Epigenome CD4+ CD25+ CD127- Treg Primary Cells Summary for 7 assay type(s)  
CD4+ CD25- CD45RA+ Naive Primary Cells Summary  Roadmap Epigenome CD4+ CD25- CD45RA+ Naive Primary Cells Summary for 6 assay type(s)  
CD4+ CD25- CD45RO+ Memory Primary Cells Summary  Roadmap Epigenome CD4+ CD25- CD45RO+ Memory Primary Cells Summary for 6 assay type(s)  
CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Summary  Roadmap Epigenome CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Summary for 6 assay type(s)  
CD4+ CD25- IL17- PMA-Ionomycin stimulated MACS purified Th Primary Cells Summary  Roadmap Epigenome CD4+ CD25- IL17- PMA-Ionomycin stimulated MACS purified Th Primary Cells Summary for 7 assay type(s)  
CD4+ CD25- Th Primary Cells Summary  Roadmap Epigenome CD4+ CD25- Th Primary Cells Summary for 7 assay type(s)  
CD4+ CD25int CD127+ Tmem Primary Cells Summary  Roadmap Epigenome CD4+ CD25int CD127+ Tmem Primary Cells Summary for 7 assay type(s)  
CD4+CD25-M Summary  Roadmap Epigenome CD4+CD25-M Summary for 7 assay type(s)  
CD4+CD25-MACS Summary  Roadmap Epigenome CD4+CD25-MACS Summary for 6 assay type(s)  
CD4+CD25-N Summary  Roadmap Epigenome CD4+CD25-N Summary for 6 assay type(s)  
CD4+CD25-Th Summary  Roadmap Epigenome CD4+CD25-Th Summary for 6 assay type(s)  
CD4+CD25-Th17 Summary  Roadmap Epigenome CD4+CD25-Th17 Summary for 5 assay type(s)  
CD4+CD25-Tm Summary  Roadmap Epigenome CD4+CD25-Tm Summary for 3 assay type(s)  
CD4+CD25-Tr Summary  Roadmap Epigenome CD4+CD25-Tr Summary for 6 assay type(s)  
CD56 Primary Cells Summary  Roadmap Epigenome CD56 Primary Cells Summary for 8 assay type(s)  
CD8 Memory Primary Cells Summary  Roadmap Epigenome CD8 Memory Primary Cells Summary for 7 assay type(s)  
CD8 Naive Primary Cells Summary  Roadmap Epigenome CD8 Naive Primary Cells Summary for 12 assay type(s)  
CD8 Primary Cells Summary  Roadmap Epigenome CD8 Primary Cells Summary for 7 assay type(s)  
Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Summary  Roadmap Epigenome Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Summary for 9 assay type(s)  
Colon Smooth Muscle Summary  Roadmap Epigenome Colon Smooth Muscle Summary for 9 assay type(s)  
Colonic Mucosa Summary  Roadmap Epigenome Colonic Mucosa Summary for 9 assay type(s)  
Duodenum Mucosa Summary  Roadmap Epigenome Duodenum Mucosa Summary for 9 assay type(s)  
Duodenum Smooth Muscle Summary  Roadmap Epigenome Duodenum Smooth Muscle Summary for 7 assay type(s)  
ES-I3 Summary  Roadmap Epigenome ES-I3 Summary for 8 assay type(s)  
ES-WA7 Summary  Roadmap Epigenome ES-WA7 Summary for 8 assay type(s)  
Esophagus Summary  Roadmap Epigenome Esophagus Summary for 9 assay type(s)  
Fetal Adrenal Gland Summary  Roadmap Epigenome Fetal Adrenal Gland Summary for 8 assay type(s)  
Fetal Brain Summary  Roadmap Epigenome Fetal Brain Summary for 14 assay type(s)  
Fetal Heart Summary  Roadmap Epigenome Fetal Heart Summary for 10 assay type(s)  
Fetal Intestine Large Summary  Roadmap Epigenome Fetal Intestine Large Summary for 9 assay type(s)  
Fetal Intestine Small Summary  Roadmap Epigenome Fetal Intestine Small Summary for 9 assay type(s)  
Fetal Kidney Left Summary  Roadmap Epigenome Fetal Kidney Left Summary for 1 assay type(s)  
Fetal Kidney Right Summary  Roadmap Epigenome Fetal Kidney Right Summary for 1 assay type(s)  
Fetal Kidney Summary  Roadmap Epigenome Fetal Kidney Summary for 9 assay type(s)  
Fetal Lung Left Summary  Roadmap Epigenome Fetal Lung Left Summary for 2 assay type(s)  
Fetal Lung Right Summary  Roadmap Epigenome Fetal Lung Right Summary for 2 assay type(s)  
Fetal Lung Summary  Roadmap Epigenome Fetal Lung Summary for 10 assay type(s)  
Fetal Muscle Arm Summary  Roadmap Epigenome Fetal Muscle Arm Summary for 3 assay type(s)  
Fetal Muscle Back Summary  Roadmap Epigenome Fetal Muscle Back Summary for 2 assay type(s)  
Fetal Muscle Leg Summary  Roadmap Epigenome Fetal Muscle Leg Summary for 10 assay type(s)  
Fetal Muscle Lower Limb Skeletal Summary  Roadmap Epigenome Fetal Muscle Lower Limb Skeletal Summary for 2 assay type(s)  
Fetal Muscle Trunk Summary  Roadmap Epigenome Fetal Muscle Trunk Summary for 9 assay type(s)  
Fetal Muscle Upper Limb Skeletal Summary  Roadmap Epigenome Fetal Muscle Upper Limb Skeletal Summary for 2 assay type(s)  
Fetal Muscle Upper Trunk Summary  Roadmap Epigenome Fetal Muscle Upper Trunk Summary for 1 assay type(s)  
Fetal Ovary Summary  Roadmap Epigenome Fetal Ovary Summary for 2 assay type(s)  
Fetal Placenta Summary  Roadmap Epigenome Fetal Placenta Summary for 8 assay type(s)  
Fetal Renal Cortex Left Summary  Roadmap Epigenome Fetal Renal Cortex Left Summary for 1 assay type(s)  
Fetal Renal Cortex Right Summary  Roadmap Epigenome Fetal Renal Cortex Right Summary for 1 assay type(s)  
Fetal Renal Cortex Summary  Roadmap Epigenome Fetal Renal Cortex Summary for 1 assay type(s)  
Fetal Renal Pelvis Left Summary  Roadmap Epigenome Fetal Renal Pelvis Left Summary for 1 assay type(s)  
Fetal Renal Pelvis Right Summary  Roadmap Epigenome Fetal Renal Pelvis Right Summary for 1 assay type(s)  
Fetal Renal Pelvis Summary  Roadmap Epigenome Fetal Renal Pelvis Summary for 1 assay type(s)  
Fetal Skin Summary  Roadmap Epigenome Fetal Skin Summary for 1 assay type(s)  
Fetal Spinal Cord Summary  Roadmap Epigenome Fetal Spinal Cord Summary for 2 assay type(s)  
Fetal Spleen Summary  Roadmap Epigenome Fetal Spleen Summary for 1 assay type(s)  
Fetal Stomach Summary  Roadmap Epigenome Fetal Stomach Summary for 8 assay type(s)  
Fetal Testes Summary  Roadmap Epigenome Fetal Testes Summary for 1 assay type(s)  
Fetal Thymus Summary  Roadmap Epigenome Fetal Thymus Summary for 10 assay type(s)  
Fibroblasts Fetal Skin Abdomen Summary  Roadmap Epigenome Fibroblasts Fetal Skin Abdomen Summary for 2 assay type(s)  
Fibroblasts Fetal Skin Back Summary  Roadmap Epigenome Fibroblasts Fetal Skin Back Summary for 2 assay type(s)  
Fibroblasts Fetal Skin Biceps Left Summary  Roadmap Epigenome Fibroblasts Fetal Skin Biceps Left Summary for 1 assay type(s)  
Fibroblasts Fetal Skin Biceps Right Summary  Roadmap Epigenome Fibroblasts Fetal Skin Biceps Right Summary for 1 assay type(s)  
Fibroblasts Fetal Skin Quadriceps Left Summary  Roadmap Epigenome Fibroblasts Fetal Skin Quadriceps Left Summary for 1 assay type(s)  
Fibroblasts Fetal Skin Quadriceps Right Summary  Roadmap Epigenome Fibroblasts Fetal Skin Quadriceps Right Summary for 1 assay type(s)  
Fibroblasts Fetal Skin Scalp Summary  Roadmap Epigenome Fibroblasts Fetal Skin Scalp Summary for 2 assay type(s)  
Fibroblasts Fetal Skin Upper Back Summary  Roadmap Epigenome Fibroblasts Fetal Skin Upper Back Summary for 1 assay type(s)  
Gastric Summary  Roadmap Epigenome Gastric Summary for 10 assay type(s)  
H1 BMP4 Derived Mesendoderm Cultured Cells Summary  Roadmap Epigenome H1 BMP4 Derived Mesendoderm Cultured Cells Summary for 8 assay type(s)  
H1 BMP4 Derived Trophoblast Cultured Cells Summary  Roadmap Epigenome H1 BMP4 Derived Trophoblast Cultured Cells Summary for 20 assay type(s)  
H1 BMP4 Mesendoderm Summary  Roadmap Epigenome H1 BMP4 Mesendoderm Summary for 14 assay type(s)  
H1 BMP4 Trophoblast Summary  Roadmap Epigenome H1 BMP4 Trophoblast Summary for 11 assay type(s)  
H1 Derived Embryoid Body Cultured Cells Summary  Roadmap Epigenome H1 Derived Embryoid Body Cultured Cells Summary for 1 assay type(s)  
H1 Derived Mesenchymal Stem Cells Summary  Roadmap Epigenome H1 Derived Mesenchymal Stem Cells Summary for 25 assay type(s)  
H1 Derived Neuronal Progenitor Cultured Cells r1a Summary  Roadmap Epigenome H1 Derived Neuronal Progenitor Cultured Cells r1a Summary for 1 assay type(s)  
H1 Derived Neuronal Progenitor Cultured Cells r1b Summary  Roadmap Epigenome H1 Derived Neuronal Progenitor Cultured Cells r1b Summary for 1 assay type(s)  
H1 Derived Neuronal Progenitor Cultured Cells r1c Summary  Roadmap Epigenome H1 Derived Neuronal Progenitor Cultured Cells r1c Summary for 1 assay type(s)  
H1 Derived Neuronal Progenitor Cultured Cells r2a Summary  Roadmap Epigenome H1 Derived Neuronal Progenitor Cultured Cells r2a Summary for 1 assay type(s)  
H1 Derived Neuronal Progenitor Cultured Cells r2b Summary  Roadmap Epigenome H1 Derived Neuronal Progenitor Cultured Cells r2b Summary for 1 assay type(s)  
H1 Derived Neuronal Progenitor Cultured Cells Summary  Roadmap Epigenome H1 Derived Neuronal Progenitor Cultured Cells Summary for 23 assay type(s)  
H1-BMP4 Summary  Roadmap Epigenome H1-BMP4 Summary for 2 assay type(s)  
H1DNP Summary  Roadmap Epigenome H1DNP Summary for 2 assay type(s)  
H1Es Summary  Roadmap Epigenome H1Es Summary for 34 assay type(s)  
H9 Cell line Summary  Roadmap Epigenome H9 Cell line Summary for 32 assay type(s)  
H9 Derived Embryoid Body Cultured Cells Summary  Roadmap Epigenome H9 Derived Embryoid Body Cultured Cells Summary for 1 assay type(s)  
H9 Derived Neuron Cultured Cells Summary  Roadmap Epigenome H9 Derived Neuron Cultured Cells Summary for 7 assay type(s)  
H9 Derived Neuronal Progenitor Cultured Cells Summary  Roadmap Epigenome H9 Derived Neuronal Progenitor Cultured Cells Summary for 8 assay type(s)  
HDN Summary  Roadmap Epigenome HDN Summary for 1 assay type(s)  
HDNP Summary  Roadmap Epigenome HDNP Summary for 1 assay type(s)  
Heart Summary  Roadmap Epigenome Heart Summary for 1 assay type(s)  
hESC Derived CD184 Endoderm Cultured Cells Summary  Roadmap Epigenome hESC Derived CD184 Endoderm Cultured Cells Summary for 1 assay type(s)  
hESC Derived CD184+ Endoderm Cultured Cells Summary  Roadmap Epigenome hESC Derived CD184+ Endoderm Cultured Cells Summary for 10 assay type(s)  
hESC Derived CD56+ Ectoderm Cultured Cells Summary  Roadmap Epigenome hESC Derived CD56+ Ectoderm Cultured Cells Summary for 9 assay type(s)  
hESC Derived CD56+ Mesoderm Cultured Cells Summary  Roadmap Epigenome hESC Derived CD56+ Mesoderm Cultured Cells Summary for 9 assay type(s)  
HUES1 Derived Embryoid Body Cultured Cells Summary  Roadmap Epigenome HUES1 Derived Embryoid Body Cultured Cells Summary for 1 assay type(s)  
HUES1 Summary  Roadmap Epigenome HUES1 Summary for 1 assay type(s)  
HUES13 Summary  Roadmap Epigenome HUES13 Summary for 1 assay type(s)  
HUES28 Summary  Roadmap Epigenome HUES28 Summary for 1 assay type(s)  
HUES3 Derived Embryoid Body Cultured Cells Summary  Roadmap Epigenome HUES3 Derived Embryoid Body Cultured Cells Summary for 1 assay type(s)  
HUES3 Summary  Roadmap Epigenome HUES3 Summary for 1 assay type(s)  
HUES44 Summary  Roadmap Epigenome HUES44 Summary for 1 assay type(s)  
HUES45 Derived Embryoid Body Cultured Cells Summary  Roadmap Epigenome HUES45 Derived Embryoid Body Cultured Cells Summary for 1 assay type(s)  
HUES45 Summary  Roadmap Epigenome HUES45 Summary for 1 assay type(s)  
HUES48 Summary  Roadmap Epigenome HUES48 Summary for 9 assay type(s)  
HUES49 Summary  Roadmap Epigenome HUES49 Summary for 1 assay type(s)  
HUES53 Summary  Roadmap Epigenome HUES53 Summary for 1 assay type(s)  
HUES6 Derived Embryoid Body Cultured Cells Summary  Roadmap Epigenome HUES6 Derived Embryoid Body Cultured Cells Summary for 1 assay type(s)  
HUES6 Summary  Roadmap Epigenome HUES6 Summary for 9 assay type(s)  
HUES62 Summary  Roadmap Epigenome HUES62 Summary for 1 assay type(s)  
HUES63 Summary  Roadmap Epigenome HUES63 Summary for 1 assay type(s)  
HUES64 Summary  Roadmap Epigenome HUES64 Summary for 11 assay type(s)  
HUES65 Summary  Roadmap Epigenome HUES65 Summary for 1 assay type(s)  
HUES66 Summary  Roadmap Epigenome HUES66 Summary for 1 assay type(s)  
HUES8 Summary  Roadmap Epigenome HUES8 Summary for 1 assay type(s)  
HUES9 Summary  Roadmap Epigenome HUES9 Summary for 1 assay type(s)  
IMR90 Summary  Roadmap Epigenome IMR90 Summary for 33 assay type(s)  
iPS DF 19 11 Summary  Roadmap Epigenome iPS DF 19 11 Summary for 8 assay type(s)  
iPS DF 19 7 Summary  Roadmap Epigenome iPS DF 19 7 Summary for 1 assay type(s)  
iPS DF 19 Summary  Roadmap Epigenome iPS DF 19 Summary for 1 assay type(s)  
iPS DF 4 7 Summary  Roadmap Epigenome iPS DF 4 7 Summary for 1 assay type(s)  
iPS DF 6 9 Summary  Roadmap Epigenome iPS DF 6 9 Summary for 8 assay type(s)  
iPS-DF.19.11 Summary  Roadmap Epigenome iPS-DF.19.11 Summary for 1 assay type(s)  
iPS-DF.6.9 Summary  Roadmap Epigenome iPS-DF.6.9 Summary for 1 assay type(s)  
iPS11a Summary  Roadmap Epigenome iPS11a Summary for 3 assay type(s)  
iPS11b Summary  Roadmap Epigenome iPS11b Summary for 1 assay type(s)  
iPS11c Summary  Roadmap Epigenome iPS11c Summary for 1 assay type(s)  
iPS15b Summary  Roadmap Epigenome iPS15b Summary for 8 assay type(s)  
iPS17a Summary  Roadmap Epigenome iPS17a Summary for 1 assay type(s)  
iPS17b Summary  Roadmap Epigenome iPS17b Summary for 1 assay type(s)  
iPS18a Summary  Roadmap Epigenome iPS18a Summary for 9 assay type(s)  
iPS18b Summary  Roadmap Epigenome iPS18b Summary for 2 assay type(s)  
iPS18c Summary  Roadmap Epigenome iPS18c Summary for 7 assay type(s)  
iPS20b Summary  Roadmap Epigenome iPS20b Summary for 9 assay type(s)  
iPS27b Summary  Roadmap Epigenome iPS27b Summary for 1 assay type(s)  
iPS27e Summary  Roadmap Epigenome iPS27e Summary for 1 assay type(s)  
Left Ventricle Summary  Roadmap Epigenome Left Ventricle Summary for 9 assay type(s)  
Lung Summary  Roadmap Epigenome Lung Summary for 8 assay type(s)  
Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Summary  Roadmap Epigenome Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Summary for 7 assay type(s)  
Mobiled CD34 Summary  Roadmap Epigenome Mobiled CD34 Summary for 10 assay type(s)  
Mobilized CD3 Primary Cells Summary  Roadmap Epigenome Mobilized CD3 Primary Cells Summary for 1 assay type(s)  
Mobilized CD34 Primary Cells Summary  Roadmap Epigenome Mobilized CD34 Primary Cells Summary for 2 assay type(s)  
Mobilized CD4 Primary Cells Summary  Roadmap Epigenome Mobilized CD4 Primary Cells Summary for 2 assay type(s)  
Mobilized CD8 Primary Cells Summary  Roadmap Epigenome Mobilized CD8 Primary Cells Summary for 1 assay type(s)  
Muscle Satellite Cultured Cells Summary  Roadmap Epigenome Muscle Satellite Cultured Cells Summary for 8 assay type(s)  
Neurosphere Cultured Cells Cortex Derived Summary  Roadmap Epigenome Neurosphere Cultured Cells Cortex Derived Summary for 11 assay type(s)  
Neurosphere Cultured Cells Ganglionic Eminence Derived Summary  Roadmap Epigenome Neurosphere Cultured Cells Ganglionic Eminence Derived Summary for 12 assay type(s)  
Ovary Summary  Roadmap Epigenome Ovary Summary for 8 assay type(s)  
Pancreas Summary  Roadmap Epigenome Pancreas Summary for 10 assay type(s)  
Pancreatic Islets Summary  Roadmap Epigenome Pancreatic Islets Summary for 10 assay type(s)  
PBM Summary  Roadmap Epigenome PBM Summary for 8 assay type(s)  
Penis Foreskin Fibroblast Primary Cells Summary  Roadmap Epigenome Penis Foreskin Fibroblast Primary Cells Summary for 13 assay type(s)  
Penis Foreskin Keratinocyte Primary Cells Summary  Roadmap Epigenome Penis Foreskin Keratinocyte Primary Cells Summary for 14 assay type(s)  
Penis Foreskin Melanocyte Primary Cells Summary  Roadmap Epigenome Penis Foreskin Melanocyte Primary Cells Summary for 13 assay type(s)  
PenisF Summary  Roadmap Epigenome PenisF Summary for 1 assay type(s)  
PenisM Summary  Roadmap Epigenome PenisM Summary for 1 assay type(s)  
Peripheral Blood Mononuclear Primary Cells Summary  Roadmap Epigenome Peripheral Blood Mononuclear Primary Cells Summary for 9 assay type(s)  
PFKPC Summary  Roadmap Epigenome PFKPC Summary for 5 assay type(s)  
Placenta Amnion Summary  Roadmap Epigenome Placenta Amnion Summary for 8 assay type(s)  
Placenta Basal Plate Summary  Roadmap Epigenome Placenta Basal Plate Summary for 1 assay type(s)  
Placenta Chorion Smooth Summary  Roadmap Epigenome Placenta Chorion Smooth Summary for 7 assay type(s)  
Placenta Trophoblast Primary Cells Summary  Roadmap Epigenome Placenta Trophoblast Primary Cells Summary for 1 assay type(s)  
Placenta Villi Summary  Roadmap Epigenome Placenta Villi Summary for 1 assay type(s)  
Primary Fibroblast Summary  Roadmap Epigenome Primary Fibroblast Summary for 1 assay type(s)  
Psoas Muscle Summary  Roadmap Epigenome Psoas Muscle Summary for 9 assay type(s)  
Rectal Mucosa Summary  Roadmap Epigenome Rectal Mucosa Summary for 9 assay type(s)  
Rectal Smooth Muscle Summary  Roadmap Epigenome Rectal Smooth Muscle Summary for 9 assay type(s)  
Right Atrium Summary  Roadmap Epigenome Right Atrium Summary for 7 assay type(s)  
Right Ventricle Summary  Roadmap Epigenome Right Ventricle Summary for 8 assay type(s)  
Sigmoid Colon Summary  Roadmap Epigenome Sigmoid Colon Summary for 9 assay type(s)  
Skeletal Muscle Summary  Roadmap Epigenome Skeletal Muscle Summary for 2 assay type(s)  
Small Intestine Summary  Roadmap Epigenome Small Intestine Summary for 10 assay type(s)  
Spleen Summary  Roadmap Epigenome Spleen Summary for 9 assay type(s)  
StM Summary  Roadmap Epigenome StM Summary for 7 assay type(s)  
Stomach Mucosa Summary  Roadmap Epigenome Stomach Mucosa Summary for 8 assay type(s)  
Stomach Smooth Muscle Summary  Roadmap Epigenome Stomach Smooth Muscle Summary for 9 assay type(s)  
Testis Spermatozoa Primary Cells Summary  Roadmap Epigenome Testis Spermatozoa Primary Cells Summary for 1 assay type(s)  
Th17 Primary Cells Summary  Roadmap Epigenome Th17 Primary Cells Summary for 2 assay type(s)  
Thymus Summary  Roadmap Epigenome Thymus Summary for 7 assay type(s)  
Treg Primary Cells Summary  Roadmap Epigenome Treg Primary Cells Summary for 5 assay type(s)  
UCSF-4star Summary  Roadmap Epigenome UCSF-4star Summary for 8 assay type(s)  
UCSF-4Star Summary  Roadmap Epigenome UCSF-4Star Summary for 6 assay type(s)  

Vizhub @ Wash U built this track, and Roadmap Epigenomics Consortium is responsible for its contents.

Description

These tracks are genome-wide DNA methylation maps generated by Roadmap Epigenomics Project. Each track is collection of DNA methylation experiment data on one sample type.

DNA methylation of human DNA mostly happens on cytosine bases of CpG dinucleotides. The methylated DNA usually prevent accessibility of regulatory proteins and hampers transcription, while unmethylated DNA is usually indicative of open chromatin. The MeDIP-Seq and MRE-Seq experiments are usually performed on same sample to identify genome-wide DNA methylation pattern. MeDIP-Seq (methylated DNA immunoprecipitation and sequencing) is a ChIP-based approach utilizing antibody against methylated cytosine. This method enriches methylated DNA and high read count indicates high likelihood of underlying region is methylated. The MRE-Seq (methylation restriction enzyme sequencing) uses methylation-sensitive restriction enzymes to digest DNA, and only cut at unmethylated restriction sites. The cut restriction sites will be detected by sequencing where reads aligned to a restriction site on reference genome means the restriction site is unmethylated.

The MethylC-Seq (MethylC sequencing) uses bisulfite to convert methylated cytosines to thymines before sequencing. The percentage of reads with a T versus a C indicates the percentage methylation at the cytosine. Details can be found in this paper Lister R, et al., Nature. 2009 Nov 19;462(7271):315-22. .

RRBS (Reduced-Representation-Bisulfite-Sequencing) is similar to MethylC-seq except RRBS uses restriction enzyme to fragment the genome into fragments suitably-sized for sequencing. While RRBS produces percent methylation similar to MethylC-seq, it is limited to cytosines that are within restriction fragments of a suitable size and tend to measure CpG dense regions only. Details can be found in this paper: Meissener, A. et al., Nucleic Acids Res. 2005; 33(18): 5868-5877. .

Display conventions

Each track can be turned on/off individually. Inside each track, sub-tracks are displayed in same vertical space and are overlayed with transparent colors for contrast. All tracks displays read density data in form of wiggle plots. Number of aligned reads is counted at each base pair, and a summarized value is computed for each 20 bp interval for display. Sub-tracks sharing same space use same scale.

Methods

Experimental protocols: follow this link for experimental protocols.

Data processing: EDACC carried out data processing and quality assessment. Details are fully explained here . In brief, sequencing reads were aligned with 'Pash' program to derive read density data. The read density data is prepared into 'wiggle' format files with fixed step length of 20 bp. Data in wiggle and other formats have been deposited in NCBI Gene Expression Omnibus database for public access.

Quality control: the HotSpot was one of the methods used to assess quality of MeDIP-Seq experiments. The long track name includes a "Hotspot_Score" field indicates the percentage of sequencing reads found inside hotspot regions. The "Pcnt" field shows the percentile of current experiment score in all MeDIP-Seq experiments. This value is subject to change in next Data Release. The most comprehensive and up-to-date description on QC Metrics used by the consortium can be found here .

Release Notes

The data is combination of Release II, III, IV, V, VI, VII, VIII and IX which were mapped to human reference genome version hg19. The data is production of Roadmap Epigenomics Project.

Please follow the link for Roadmap Epigenomics data access policy

Credits

These data were generated in labs from three institutions: UCSF, UBC, UCSD as part of Roadmap Epigenomics Project.

Useful links