The Modern Human Seq track shows human sequence reads of seven individuals mapped
to the human genome. The purpose of this track is to put the divergence of the
Denisova genome into perspective with regard to present-day humans.
DNA was obtained for each of seven individuals from the CEPH-Human
Genome Diversity Panel (HGDP): HGDP00456 (Mbuti), HGDP00998 (Karitiana
Native American), HGDP00665 (Sardinia), HGDP00491 (Bougainville
Melanesian), HGDP00711 (Cambodian), HGDP01224 (Mongolian) and
HGDP00551 (Papuan). Each library was sequenced on the Illumina Genome
Analyzer IIx using 2x101 + 7 cycles on one flow cell according to the
manufacturer's instructions for multiplex sequencing. The paired-end
reads were aligned
using the Burrows-Wheeler Aligner to the human sequence (NCBI36/hg18)
Modern Human Seq track data sets from the Genome Browser downloads server.
Briggs A.W., Stenzel U., Meyer M., Krause J., Kircher M., Pääbo S.
Removal of deaminated cytosines and detection of in vivo
methylation in ancient DNA.
Nucleic Acids Res. 2009 Dec 22:38(6) e87.
Reich D., Green R.E., Kircher M., Krause J., Patterson N., Durand E.Y., Viola B.,
Briggs A.W., Stenzel U., Johnson P.L.F. et al.
Genetic history of an archaic hominin group from Denisova Cave in Siberia.
Nature. 2010 Dec 23;468:1053-1060.
This track was produced at UCSC using data generated by the Max Planck
Institute for Evolutionary Anthropology.