This track provides the location of genomic regions that show differential
DNA methylation (DNAm) between induced pluripotent stem (iPS) cells and their parental fibroblasts.
M values represent averaged methylation values across all samples in a given cell type. R-DMRs were
identified using Comprehensive High-Throughput Arrays for Relative Methylation (CHARM) analysis. For
a detailed description of CHARM analysis, please see Irizarry RA et al., 2008.
Thanks to Andrew P. Feinberg and Christine Ladd-Acosta for providing this
Doi A, Park IH, Wen B, Murakami P, Aryee MJ, Irizarry R, Herb B, Ladd-Acosta
C, Rho J, Loewer S, Miller J, Schlaeger T, Daley GQ, Feinberg AP. Differential
methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent
stem cells, embryonic stem cells and fibroblasts. Nature Genetics 2009
Irizarry RA, Ladd-Acosta C, Carvalho B, Wu H, Brandenburg SA, Jeddeloh JA, Wen B, Feinberg AP.
arrays for relative methylation (CHARM). Genome Research 2008 May;18(5):780-90.