Uppsala ChIP Tracks
 
Uppsala University ChIP-chip tracks   (All Regulation tracks)

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UU ChIP Signal  Uppsala University ChIP-chip Signal  
UU ChIP Sites  Uppsala University ChIP-chip Sites  

Overview

This super-track combines related tracks of genome-wide ChIP-chip data generated by the Wadelius lab at Uppsala University, Sweden. These tracks display localization of two transcription factors (USF1 and USF2) and acetylated histone H3 (H3ac) in a liver cell line (HepG2), as assayed by Affymetrix arrays tiled at 35 bp resolution. For each factor, the average probe level intensities as well as identified positive regions are presented.

The raw data for these tracks is available at EBI ArrayExpress, as experiment E-TABM-314.

Credits

These experiments were performed in the Claes Wadelius lab Dept. of Genetics and Pathology, Uppsala University, Sweden. Microarray hybridizations were performed at Affymetrix Inc., Santa Clara, USA. Data processing and statistical analysis was done at The Linnaeus Centre for Bioinformatics, Uppsala University, Sweden.

References

Rada-Iglesias A, Ameur A, Kapranov P, Enroth S, Komorowski J, Gingeras TR, Wadelius C. Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders. Genome Res. 2008 Mar;18(3):380-92.

Rada-Iglesias A, Wallerman O, Koch C, Ameur A, Enroth S, Clelland G, Wester K, Wilcox S, Dovey OM, Ellis PD et. al. Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays. Hum Mol Genet. 2005 Nov 15;14(22):3435-47.