RGD QTL Track Settings
 
Quantitative Trait Locus (from RGD)   (All Phenotype and Disease Associations tracks)

Display mode:      Duplicate track
Data schema/format description and download
Assembly: Human May 2004 (NCBI35/hg17)
Data last updated at UCSC: 2006-06-21

Description

A quantitative trait locus (QTL) is a polymorphic locus that contains alleles which differentially affect the expression of a continuously distributed phenotypic trait. Usually a QTL is a marker described by statistical association to quantitative variation in the particular phenotypic trait that is thought to be controlled by the cumulative action of alleles at multiple loci.

For a comprehensive review of QTL mapping techniques in the rat, see Rapp, J. (2000). Genetic Analysis of Inherited Hypertension in the Rat. Physiol. Rev., 90:135-172.

Methods

The annotation data file, human_QTL.gff, was downloaded from:

       ftp://rgd.mcw.edu/pub/RGD_genome_annotations/human/archive/human_QTL.gff.020805

and processed to create two UCSC Genome Browser tables — rgdQtl and rgdQtlLink — to enable this track.

Credits

Thanks to the RGD for providing this annotation. RGD is funded by grant HL64541 entitled "Rat Genome Database", awarded to Dr. Howard J Jacob, Medical College of Wisconsin, from the National Heart Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH).