Description
A quantitative trait locus (QTL) is a polymorphic locus that contains alleles
which differentially affect the expression of a continuously distributed
phenotypic trait. Usually a QTL is a marker described by statistical association
to quantitative variation in the particular phenotypic trait that is thought to
be controlled by the cumulative action of alleles at multiple loci.
For a comprehensive review of QTL mapping techniques in the rat, see Rapp, J.
(2000).
Genetic Analysis of Inherited Hypertension in the Rat.
Physiol. Rev., 90:135-172.
Methods
The annotation data file, human_QTL.gff, was downloaded from:
      
ftp://rgd.mcw.edu/pub/RGD_genome_annotations/human/archive/human_QTL.gff.020805
and processed to create two UCSC Genome Browser tables — rgdQtl and rgdQtlLink
— to enable this track.
Credits
Thanks to the RGD for providing
this annotation. RGD is funded by grant HL64541 entitled "Rat Genome Database",
awarded to Dr. Howard J Jacob, Medical College of Wisconsin, from the National
Heart Lung and Blood Institute
(NHLBI) of the National
Institutes of Health (NIH).
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