Description

This track depicts human-cattle synteny segments as defined on the basis of a cattle-human comparative map containing 3,200 BAC-end sequences and EST markers with a single significant hit (E-value less than 0.00001) in the human genome sequence (hg15) as defined by the TimeLogic Tera-BLASTn program (Everts-van der Wind et al., 2005). The synteny blocks were defined according to the rules described in Murphy et al. (2005).

Credits

Thanks to Harris Lewin, Denis Larkin, and Annelie Everts-van der Wind, University of Illinois at Urbana-Champaign, for providing these data.

References

Everts-van der Wind, A., Larkin, D., Green, C., Elliott, J., Olmstead, C., Chiu, R., Schein, J., Marra, M., Womack, J., and Lewin, H. A high-resolution whole-genome cattle-human comparative map reveals details of mammalian chromosome evolution. Proc Natl Acad Sci 102(51) 18526-18531 (2005).

Murphy, W., Larkin, D., Everts-van der Wind, A., Bourque, G., Tesler, G., Auvil, L., Beever, J., Chowdhary, B., Galibert, F., Gatzke, L., Hitte, C., Meyers, S., Milan, D., Ostrander, E., Pape, G., Parker, H., Raudsepp, T., Rogatcheva, M., Schook, L., Skow, L., Welge, M., Womack, J., O'Brien, S., Pevzner, P., and Lewin, H. Dynamics of Mammalian Chromosome Evolution Inferred from Multispecies Comparative Maps. Science 309(5734) 613-617 (2005).