Layered H3K27Ac Track Settings
 
H3K27Ac Mark (Often Found Near Regulatory Elements) on 7 cell lines from ENCODE   (ENCODE Regulation)

This track is part of a parent called ENCODE Regulation. To show other tracks of this parent, go to the ENCODE Regulation configuration page.

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     GM12878  H3K27Ac Mark (Often Found Near Regulatory Elements) on GM12878 Cells from ENCODE   Schema 
     H1-hESC  H3K27Ac Mark (Often Found Near Regulatory Elements) on H1-hESC Cells from ENCODE   Schema 
     HSMM  H3K27Ac Mark (Often Found Near Regulatory Elements) on HSMM Cells from ENCODE   Schema 
     HUVEC  H3K27Ac Mark (Often Found Near Regulatory Elements) on HUVEC Cells from ENCODE   Schema 
     K562  H3K27Ac Mark (Often Found Near Regulatory Elements) on K562 Cells from ENCODE   Schema 
     NHEK  H3K27Ac Mark (Often Found Near Regulatory Elements) on NHEK Cells from ENCODE   Schema 
     NHLF  H3K27Ac Mark (Often Found Near Regulatory Elements) on NHLF Cells from ENCODE   Schema 
    
Data coordinates converted via liftOver from: Feb. 2009 (GRCh37/hg19)


Note: lifted from hg19
p12 Note: includes annotations on GRCh38.p12 patch sequences

Description

Chemical modifications (e.g., methylation and acetylation) to the histone proteins present in chromatin influence gene expression by changing how accessible the chromatin is to transcription. A specific modification of a specific histone protein is called a histone mark. This track shows the levels of enrichment of the H3K27Ac histone mark across the genome as determined by a ChIP-seq assay. The H3K27Ac histone mark is the acetylation of lysine 27 of the H3 histone protein, and it is thought to enhance transcription possibly by blocking the spread of the repressive histone mark H3K27Me3. Additional histone marks and other chromatin associated ChIP-seq data is available at the Broad Histone page.

Display Conventions and Configuration

By default, this track uses a transparent overlay method of displaying data from a number of cell lines in the same vertical space. Each of the cell lines in this track is associated with a particular color, and these colors are relatively light and saturated so as to work best with the transparent overlay. The color of these tracks match their versions from their lifted source on the hg19 assembly. The colors are consistent with the other hg19 lifted tracks located in the ENCODE Regulation supertrack, with the exception being the DNase tracks, as they were not lifted from hg19 and are colored to reflect similarity of cell types.

Credits

This track shows data from the Bernstein Lab at the Broad Institute, as part of the ENCODE Consortium.

Data Release Policy

Primary ENCODE data produced during the 2007-2012 production phase were subject to a restriction period. However, the data here are past those restrictions and are freely available. The full data release policy for ENCODE is available here.