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BC012761 Alignments in mRNAs

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 SIZE IDENTITY CHROMOSOME STRAND  START     END       cDNA   START  END  TOTAL
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 2580   99.9%          9     + 124257970 124352440  BC012761     1  2580  2596

Mammalian Gene Collection Full ORF mRNAs

BC012761 at chr9:124257970-124352440

Gencode Genes

NEK6 (ENST00000373603.5) at chr9:124257606-124353307 - Protein kinase which plays an important role in mitotic  cell cycle progression. Required for chromosome segregation at  metaphase-anaphase transition, robust mitotic spindle formation  and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6,  RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates  KIF11 to promote mitotic spindle formation. Involved in G2/M phase  cell cycle arrest induced by DNA damage. Inhibition of activity  results in apoptosis. May contribute to tumorigenesis by  suppressing p53/TP53-induced cancer cell senescence. (from UniProt Q9HC98)
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