Non-Mouse RefSeq Gene
 

Non-Mouse RefSeq Gene IFNGR1

RefSeq: NM_000416.3   Status: Reviewed
Description: Homo sapiens interferon gamma receptor 1 (IFNGR1), transcript variant 1, mRNA.
Organism: Homo sapiens
UCSC browser: NM_000416 on Human (hg38)
CDS: 3' complete
OMIM: 107470
Entrez Gene: 3459
PubMed on Gene: IFNGR1
PubMed on Product: interferon gamma receptor 1 isoform 1 precursor

Summary of IFNGR1

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008].


mRNA/Genomic Alignments

BROWSER | SIZE IDENTITY CHROMOSOME  STRAND    START     END              QUERY      START  END  TOTAL
-----------------------------------------------------------------------------------------------------
browser |   522   73.4%         10     ++  19601399  19609760             NM_000416   347  1598  2074

Position: chr10:19601399-19609760
Band: 10qA3
Genomic Size: 8362
Strand: +
Gene Symbol: IFNGR1
CDS Start: not complete
CDS End: complete

Links to sequence:

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Data last updated at UCSC: 2020-08-17

Description

This track shows known protein-coding and non-protein-coding genes for organisms other than mouse, taken from the NCBI RNA reference sequences collection (RefSeq). The data underlying this track are updated weekly.

Display Conventions and Configuration

This track follows the display conventions for gene prediction tracks. The color shading indicates the level of review the RefSeq record has undergone: predicted (light), provisional (medium), reviewed (dark).

The item labels and display colors of features within this track can be configured through the controls at the top of the track description page.

  • Label: By default, items are labeled by gene name. Click the appropriate Label option to display the accession name instead of the gene name, show both the gene and accession names, or turn off the label completely.
  • Codon coloring: This track contains an optional codon coloring feature that allows users to quickly validate and compare gene predictions. To display codon colors, select the genomic codons option from the Color track by codons pull-down menu. Click here for more information about this feature.
  • Hide non-coding genes: By default, both the protein-coding and non-protein-coding genes are displayed. If you wish to see only the coding genes, click this box.

Methods

The RNAs were aligned against the mouse genome using blat; those with an alignment of less than 15% were discarded. At least 40 bases must be aligned to DNA that is not repeat masked. When a single RNA aligned in multiple places, the alignment having the highest base identity was identified. Only alignments having a base identity level within 1.0% of the best and at least 35% base identity with the genomic sequence were kept.

Credits

This track was produced at UCSC from RNA sequence data generated by scientists worldwide and curated by the NCBI RefSeq project.

References

Kent WJ. BLAT--the BLAST-like alignment tool. Genome Res. 2002 Apr;12(4):656-64. PMID: 11932250; PMC: PMC187518