UCSC Genome Bioinformatics
Genome Browser
Blat
Table Browser
Gene Sorter
In Silico PCR
Genome Graphs
Galaxy
VisiGene
Utilities
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  About the UCSC Genome Bioinformatics Site

Welcome to the UCSC Genome Browser website. This site contains the reference sequence and working draft assemblies for a large collection of genomes. It also provides portals to ENCODE data at UCSC (2003 to 2012) and to the Neandertal project. Download or purchase the Genome Browser source code, or the Genome Browser in a Box (GBiB) at our online store.

We encourage you to explore these sequences with our tools. The Genome Browser zooms and scrolls over chromosomes, showing the work of annotators worldwide. The Gene Sorter shows expression, homology and other information on groups of genes that can be related in many ways. Blat quickly maps your sequence to the genome. The Table Browser provides convenient access to the underlying database. VisiGene lets you browse through a large collection of in situ mouse and frog images to examine expression patterns. Genome Graphs allows you to upload and display genome-wide data sets.

The UCSC Genome Browser is developed and maintained by the Genome Bioinformatics Group, a cross-departmental team within the UC Santa Cruz Genomics Institute at the University of California Santa Cruz (UCSC). If you have feedback or questions concerning the tools or data on this website, feel free to contact us on our public mailing list.

The Genome Browser project team relies on public funding to support our work. Donations are welcome -- we have many more ideas than our funding supports! If you have ideas, drop a comment in our suggestion box.

Give to the UCSC Genome Browser

  NewsFollow @GenomeBrowser on Twitter Genome Browser Facebook page

To receive announcements of new genome assembly releases, new software features, updates and training seminars by email, subscribe to the genome-announce mailing list. Please see our blog for posts about Genome Browser tools, features, projects and more.


12 August 2015 — New blog post: How to share your UCSC screenthoughts

Do you want to save your UCSC Browser screenthoughts, or share them with a colleague, or make a slide for a talk, or publish them in a paper? Saving the state of your screen can take two forms: static or dynamic. You can snap and save a picture of the screen, or you can share a link to an active Genome Browser. We talk about both approaches here and discuss some of the advantages and pitfalls of each.


29 June 2015 — GENCODE Genes Now the Default Gene Set on the Human (GRCh38/hg38) Assembly

In a move towards standardizing on a common gene set within the bioinformatics community, UCSC has made the decision to adopt the GENCODE set of gene models as our default gene set on the human genome assembly. Today we have released the GENCODE v22 comprehensive gene set as our default gene set on human genome assembly GRCh38 (hg38), replacing the previous default UCSC Genes set generated by UCSC. To facilitate this transition, the new gene set employs the same familiar UCSC Genes schema, using nearly all the same table names and fields that have appeared in earlier versions of the UCSC set.

By default, the browser displays only the transcripts tagged as "basic" by the GENCODE Consortium. These may be found in the track labeled "GENCODE Basic" in the Genes and Gene Predictions track group. However, all the transcripts in the GENCODE comprehensive set are present in the tables, and may be viewed by adjusting the track configuration settings for the All GENCODE super-track. The most recent version of the UCSC-generated genes can still be accessed in the track "Old UCSC Genes".

The new release has 195,178 total transcripts, compared with 104,178 in the previous version. The total number of canonical genes has increased from 48,424 to 49,534. Comparing the new gene set with the previous version:

  • 9,459 transcripts did not change.
  • 22,088 transcripts were not carried forward to the new version.
  • 43,681 transcripts are "compatible" with those in the previous set, meaning that the two transcripts show consistent splicing. In most cases, the old and new transcripts differ in the lengths of their UTRs.
  • 28,950 transcripts overlap with those in the previous set, but do not show consistent splicing (i.e., they contain overlapping introns with differing splice sites)

More details about the new GENCODE Basic track can be found on the GENCODE Basic track description page.


26 June 2015 — New Bonobo (panPan1) Assembly Now Available in the Genome Browser: We are pleased to announce the release of a Genome Browser for the May 2012 assembly of bonobo, Pan paniscus (Max-Planck Institute panpan1, UCSC version panPan1). Read more.

12 June 2015 — Data Integrator: Have you ever wished that the Table Browser could associate your custom track items with some other track, while retaining the item names from both? We have released a new tool that can do just that, and more: the Data Integrator. Read more.


  Conditions of Use

The Genome Browser software, sequence and annotation data are freely available for use with these conditions. A license is required for commercial use of the software. For assistance with questions or problems regarding the UCSC Genome Browser software, database, genome assemblies, or release cycles, click here.

Program-driven use of this software is limited to a maximum of one hit every 15 seconds and no more than 5,000 hits per day.

The UCSC Genome Browser was created by the Genome Bioinformatics Group of UC Santa Cruz. Software Copyright (c) The Regents of the University of California. All rights reserved.