The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q4ADV7-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
LF385283 - JP 2014500723-A/192786: Polycomb-Associated Non-Coding RNAs. LF385475 - JP 2014500723-A/192978: Polycomb-Associated Non-Coding RNAs. AL136875 - Homo sapiens mRNA; cDNA DKFZp434D105 (from clone DKFZp434D105). BC136616 - Homo sapiens KIAA1432, mRNA (cDNA clone MGC:168229 IMAGE:9020606), complete cds. BC144296 - Homo sapiens KIAA1432, mRNA (cDNA clone MGC:177833 IMAGE:9052816), complete cds. AB205401 - Homo sapiens CIP150 mRNA for connexin43-interacting protein of 150 kDa, complete cds. AK124394 - Homo sapiens cDNA FLJ42403 fis, clone ASTRO3000177, weakly similar to Drosophila melanogaster BcDNA.GH03694 (BcDNA.GH03694) mRNA. AK022642 - Homo sapiens cDNA FLJ12580 fis, clone NT2RM4001116, weakly similar to HYPOTHETICAL 216.3 KD PROTEIN R06F6.8 IN CHROMOSOME II. AB037853 - Homo sapiens mRNA for KIAA1432 protein, partial cds. AB527173 - Synthetic construct DNA, clone: pF1KA1432, Homo sapiens KIAA1432 gene for KIAA1432, without stop codon, in Flexi system. AK074150 - Homo sapiens mRNA for FLJ00223 protein. BC030576 - Homo sapiens KIAA1432, mRNA (cDNA clone IMAGE:4077122), partial cds. MA620860 - JP 2018138019-A/192786: Polycomb-Associated Non-Coding RNAs. MA621052 - JP 2018138019-A/192978: Polycomb-Associated Non-Coding RNAs. JD109793 - Sequence 90817 from Patent EP1572962. JD468950 - Sequence 449974 from Patent EP1572962. JD428544 - Sequence 409568 from Patent EP1572962. JD206490 - Sequence 187514 from Patent EP1572962. JD301616 - Sequence 282640 from Patent EP1572962. JD154748 - Sequence 135772 from Patent EP1572962. JD315186 - Sequence 296210 from Patent EP1572962. LF345332 - JP 2014500723-A/152835: Polycomb-Associated Non-Coding RNAs. JD079965 - Sequence 60989 from Patent EP1572962. JD186607 - Sequence 167631 from Patent EP1572962. LF345335 - JP 2014500723-A/152838: Polycomb-Associated Non-Coding RNAs. JD091887 - Sequence 72911 from Patent EP1572962. LF345342 - JP 2014500723-A/152845: Polycomb-Associated Non-Coding RNAs. MA580909 - JP 2018138019-A/152835: Polycomb-Associated Non-Coding RNAs. MA580912 - JP 2018138019-A/152838: Polycomb-Associated Non-Coding RNAs. MA580919 - JP 2018138019-A/152845: Polycomb-Associated Non-Coding RNAs. LF345345 - JP 2014500723-A/152848: Polycomb-Associated Non-Coding RNAs. DQ570742 - Homo sapiens piRNA piR-30854, complete sequence. MA580922 - JP 2018138019-A/152848: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q4ADV7 (Reactome details) participates in the following event(s):
R-HSA-6811428 RIC1:RGP1 recruits RAB6:GDP to the TGN R-HSA-8847887 RAB33B:GTP binds RIC1:RGP1 R-HSA-6811431 RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles R-HSA-6811429 RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange R-HSA-8876193 RIC1-RGP1 exchanges GTP for GDP on RAB6 R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network R-HSA-6811438 Intra-Golgi traffic R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs R-HSA-199991 Membrane Trafficking R-HSA-9007101 Rab regulation of trafficking R-HSA-5653656 Vesicle-mediated transport