The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O15296
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005506 iron ion binding GO:0005509 calcium ion binding GO:0008289 lipid binding GO:0016165 linoleate 13S-lipoxygenase activity GO:0016491 oxidoreductase activity GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0036403 arachidonate 8(S)-lipoxygenase activity GO:0046872 metal ion binding GO:0050473 arachidonate 15-lipoxygenase activity GO:0051213 dioxygenase activity
Biological Process: GO:0006629 lipid metabolic process GO:0006915 apoptotic process GO:0008285 negative regulation of cell proliferation GO:0010744 positive regulation of macrophage derived foam cell differentiation GO:0019369 arachidonic acid metabolic process GO:0019372 lipoxygenase pathway GO:0030336 negative regulation of cell migration GO:0030850 prostate gland development GO:0030856 regulation of epithelial cell differentiation GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway GO:0043651 linoleic acid metabolic process GO:0045618 positive regulation of keratinocyte differentiation GO:0045786 negative regulation of cell cycle GO:0045926 negative regulation of growth GO:0051122 hepoxilin biosynthetic process GO:0055114 oxidation-reduction process GO:0090197 positive regulation of chemokine secretion
Sequence and Links to Tools and Databases 
Microarray Expression Data 
