Human Gene BPIFB2 (ENST00000170150.4) from GENCODE V44
Description: Homo sapiens BPI fold containing family B member 2 (BPIFB2), mRNA. (from RefSeq NM_025227) RefSeq Summary (NM_025227): This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic tonsils. This gene and three other members of the LT/LBP gene family form a cluster on the long arm of chromosome 20. [provided by RefSeq, Jul 2008]. Gencode Transcript: ENST00000170150.4 Gencode Gene: ENSG00000078898.7 Transcript (Including UTRs) Position: hg38 chr20:33,007,704-33,023,703 Size: 16,000 Total Exon Count: 16 Strand: + Coding Region Position: hg38 chr20:33,008,575-33,023,383 Size: 14,809 Coding Exon Count: 15
ID:BPIB2_HUMAN DESCRIPTION: RecName: Full=BPI fold-containing family B member 2; AltName: Full=Bactericidal/permeability-increasing protein-like 1; Short=BPI-like 1; AltName: Full=Long palate, lung and nasal epithelium carcinoma-associated protein 2; AltName: Full=RYSR; Flags: Precursor; SUBCELLULAR LOCATION: Secreted (By similarity). TISSUE SPECIFICITY: Highly expressed in tonsils, especially in hypertrophic tonsils. Detected at very low levels in fetal liver. SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N4F0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0019730 antimicrobial humoral response GO:0043687 post-translational protein modification GO:0044267 cellular protein metabolic process
US Server
