ID:COX7B_HUMAN DESCRIPTION: RecName: Full=Cytochrome c oxidase subunit 7B, mitochondrial; AltName: Full=Cytochrome c oxidase polypeptide VIIb; Flags: Precursor; FUNCTION: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. SUBCELLULAR LOCATION: Mitochondrion inner membrane (By similarity). SIMILARITY: Belongs to the cytochrome c oxidase VIIb family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF05392 - Cytochrome C oxidase chain VIIB
ModBase Predicted Comparative 3D Structure on P24311
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
BioCyc Knowledge Library PWY-3781 - aerobic respiration I (cytochrome c)
Reactome (by CSHL, EBI, and GO)
Protein P24311 (Reactome details) participates in the following event(s):
R-HSA-163214 Electron transfer from reduced cytochrome c to molecular oxygen R-HSA-611105 Respiratory electron transport R-HSA-5628897 TP53 Regulates Metabolic Genes R-HSA-163200 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. R-HSA-3700989 Transcriptional Regulation by TP53 R-HSA-1428517 The citric acid (TCA) cycle and respiratory electron transport R-HSA-212436 Generic Transcription Pathway R-HSA-1430728 Metabolism R-HSA-73857 RNA Polymerase II Transcription R-HSA-74160 Gene expression (Transcription)
Sequence and Links to Tools and Databases 
Microarray Expression Data 
