Human Gene YJU2 (ENST00000262962.12) from GENCODE V44
  Description: Homo sapiens YJU2 splicing factor homolog (YJU2), mRNA. (from RefSeq NM_018074)
Gencode Transcript: ENST00000262962.12
Gencode Gene: ENSG00000105248.16
Transcript (Including UTRs)
   Position: hg38 chr19:4,247,080-4,269,088 Size: 22,009 Total Exon Count: 8 Strand: +
Coding Region
   Position: hg38 chr19:4,247,147-4,268,696 Size: 21,550 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsPrimersRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Methods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:4,247,080-4,269,088)mRNA (may differ from genome)Protein (323 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblEntrez GeneExonPrimerGencodeGeneCardsHPRD
MalacardsMGIneXtProtPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: CCD94_HUMAN
DESCRIPTION: RecName: Full=Coiled-coil domain-containing protein 94;
SIMILARITY: Belongs to the CWC16 family.
SEQUENCE CAUTION: Sequence=AAC72949.1; Type=Frameshift; Positions=285;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 15.40 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 530.50 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -14.3067-0.213 Picture PostScript Text
3' UTR -159.80392-0.408 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007590 - CWC16

Pfam Domains:
PF04502 - Family of unknown function (DUF572)

ModBase Predicted Comparative 3D Structure on Q9BW85
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserGenome BrowserGenome BrowserGenome Browser
Gene Details    Gene Details
Gene Sorter    Gene Sorter
MGIRGDEnsemblEnsemblWormBaseSGD
Protein SequenceProtein SequenceProtein SequenceProtein SequenceProtein SequenceProtein Sequence
AlignmentAlignmentAlignmentAlignmentAlignmentAlignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding


-  Descriptions from all associated GenBank mRNAs
  AK001236 - Homo sapiens cDNA FLJ10374 fis, clone NT2RM2001936, weakly similar to 32.3 KD PROTEIN IN CWP1-MBR1 INTERGENIC REGION.
LF341703 - JP 2014500723-A/149206: Polycomb-Associated Non-Coding RNAs.
MA577280 - JP 2018138019-A/149206: Polycomb-Associated Non-Coding RNAs.
BC000561 - Homo sapiens coiled-coil domain containing 94, mRNA (cDNA clone MGC:974 IMAGE:3162278), complete cds.
JD147772 - Sequence 128796 from Patent EP1572962.
AK023988 - Homo sapiens cDNA FLJ13926 fis, clone Y79AA1000589, weakly similar to 32.3 KD PROTEIN IN CWP1-MBR1 INTERGENIC REGION.
AF091080 - Homo sapiens clone 614 unknown mRNA, complete sequence.
KJ894239 - Synthetic construct Homo sapiens clone ccsbBroadEn_03633 CCDC94 gene, encodes complete protein.
JD067180 - Sequence 48204 from Patent EP1572962.
JD159307 - Sequence 140331 from Patent EP1572962.
JD097767 - Sequence 78791 from Patent EP1572962.
JD174622 - Sequence 155646 from Patent EP1572962.
JD484784 - Sequence 465808 from Patent EP1572962.
JD162405 - Sequence 143429 from Patent EP1572962.
JD418107 - Sequence 399131 from Patent EP1572962.
JD399383 - Sequence 380407 from Patent EP1572962.
JD424055 - Sequence 405079 from Patent EP1572962.
JD145341 - Sequence 126365 from Patent EP1572962.
JD060694 - Sequence 41718 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: CCD94_HUMAN, CCDC94, ENST00000262962.1, ENST00000262962.10, ENST00000262962.11, ENST00000262962.2, ENST00000262962.3, ENST00000262962.4, ENST00000262962.5, ENST00000262962.6, ENST00000262962.7, ENST00000262962.8, ENST00000262962.9, NM_018074, O75270, Q9BW85, Q9H862, Q9NW16, uc002lzv.1, uc002lzv.2, uc002lzv.3, uc002lzv.4, uc002lzv.5, uc002lzv.6
UCSC ID: ENST00000262962.12
RefSeq Accession: NM_018074
Protein: Q9BW85 (aka CCD94_HUMAN)
CCDS: CCDS12124.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.