Human Gene TEX12 (ENST00000280358.5) Description and Page Index
  Description: Homo sapiens testis expressed 12 (TEX12), mRNA. (from RefSeq NM_031275)
RefSeq Summary (NM_031275): This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008].
Gencode Transcript: ENST00000280358.5
Gencode Gene: ENSG00000150783.10
Transcript (Including UTRs)
   Position: hg38 chr11:112,167,372-112,172,556 Size: 5,185 Total Exon Count: 5 Strand: +
Coding Region
   Position: hg38 chr11:112,169,269-112,171,916 Size: 2,648 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsPathways
Other NamesMethods
Data last updated at UCSC: 2021-01-14 15:32:12

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr11:112,167,372-112,172,556)mRNA (may differ from genome)Protein (123 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Testis-expressed sequence 12 protein;
TISSUE SPECIFICITY: Testis specific.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 8.40 RPKM in Testis
Total median expression: 15.31 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -46.80132-0.355 Picture PostScript Text
3' UTR -133.10640-0.208 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q9BXU0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0000711 meiotic DNA repair synthesis
GO:0007130 synaptonemal complex assembly

Cellular Component:
GO:0000795 synaptonemal complex
GO:0000801 central element

-  Descriptions from all associated GenBank mRNAs
  BC029506 - Homo sapiens testis expressed 12, mRNA (cDNA clone MGC:33672 IMAGE:5298531), complete cds.
AF285600 - Homo sapiens testis protein TEX12 (TEX12) mRNA, complete cds.
HQ447961 - Synthetic construct Homo sapiens clone IMAGE:100071323; CCSB002160_02 testis expressed 12 (TEX12) gene, encodes complete protein.
KJ899239 - Synthetic construct Homo sapiens clone ccsbBroadEn_08633 TEX12 gene, encodes complete protein.
CU688674 - Synthetic construct Homo sapiens gateway clone IMAGE:100018518 5' read TEX12 mRNA.
JD048425 - Sequence 29449 from Patent EP1572962.
JD171792 - Sequence 152816 from Patent EP1572962.

-  Biochemical and Signaling Pathways
  Reactome (by CSHL, EBI, and GO)

Protein Q9BXU0 (Reactome details) participates in the following event(s):

R-HSA-1221632 Meiotic synapsis
R-HSA-1500620 Meiosis
R-HSA-1474165 Reproduction
R-HSA-1640170 Cell Cycle

-  Other Names for This Gene
  Alternate Gene Symbols: A6NDL9, B0YIX3, ENST00000280358.1, ENST00000280358.2, ENST00000280358.3, ENST00000280358.4, NM_031275, Q9BXU0, TEX12_HUMAN, uc001pnc.1, uc001pnc.2, uc001pnc.3, uc001pnc.4, uc001pnc.5
UCSC ID: ENST00000280358.5
RefSeq Accession: NM_031275
Protein: Q9BXU0 (aka TEX12_HUMAN or TX12_HUMAN)
CCDS: CCDS31679.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.