Human Gene SLC25A36 (ENST00000324194.11) Description and Page Index
  Description: Homo sapiens solute carrier family 25 member 36 (SLC25A36), transcript variant 1, mRNA. (from RefSeq NM_001104647)
Gencode Transcript: ENST00000324194.11
Gencode Gene: ENSG00000114120.13
Transcript (Including UTRs)
   Position: hg38 chr3:140,941,836-140,980,978 Size: 39,143 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg38 chr3:140,942,055-140,976,453 Size: 34,399 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr3:140,941,836-140,980,978)mRNA (may differ from genome)Protein (311 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: S2536_HUMAN
DESCRIPTION: RecName: Full=Solute carrier family 25 member 36;
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein (By similarity).
TISSUE SPECIFICITY: Expressed at moderate level.
SIMILARITY: Belongs to the mitochondrial carrier family.
SIMILARITY: Contains 3 Solcar repeats.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 23.14 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 571.15 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -126.60219-0.578 Picture PostScript Text
3' UTR -1049.204525-0.232 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002067 - Mit_carrier
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom

Pfam Domains:
PF00153 - Mitochondrial carrier protein

ModBase Predicted Comparative 3D Structure on Q96CQ1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologGenome BrowserGenome BrowserGenome Browser
Gene Details    Gene Details
Gene Sorter    Gene Sorter
Protein SequenceProtein Sequence Protein SequenceProtein SequenceProtein Sequence
AlignmentAlignment AlignmentAlignmentAlignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0015218 pyrimidine nucleotide transmembrane transporter activity

Biological Process:
GO:0000002 mitochondrial genome maintenance
GO:0006839 mitochondrial transport
GO:0006864 pyrimidine nucleotide transport
GO:0007005 mitochondrion organization
GO:0051881 regulation of mitochondrial membrane potential
GO:0055085 transmembrane transport
GO:1990519 mitochondrial pyrimidine nucleotide import

Cellular Component:
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane

-  Descriptions from all associated GenBank mRNAs
  LF384586 - JP 2014500723-A/192089: Polycomb-Associated Non-Coding RNAs.
MA620163 - JP 2018138019-A/192089: Polycomb-Associated Non-Coding RNAs.
AK001480 - Homo sapiens cDNA FLJ10618 fis, clone NT2RP2005465, weakly similar to MITOCHONDRIAL CARRIER PROTEIN RIM2.
JD406915 - Sequence 387939 from Patent EP1572962.
AL136803 - Homo sapiens mRNA; cDNA DKFZp434M1820 (from clone DKFZp434M1820).
BC014064 - Homo sapiens solute carrier family 25, member 36, mRNA (cDNA clone MGC:19966 IMAGE:3842022), complete cds.
GQ891457 - Homo sapiens clone HEL-S-178 epididymis secretory sperm binding protein mRNA, complete cds.
BC019859 - Homo sapiens solute carrier family 25, member 36, mRNA (cDNA clone IMAGE:4452654).
BC036272 - Homo sapiens solute carrier family 25, member 36, mRNA (cDNA clone IMAGE:4403241).
JD467275 - Sequence 448299 from Patent EP1572962.
AK296785 - Homo sapiens cDNA FLJ55091 complete cds, highly similar to Homo sapiens solute carrier family 25, member 36 (SLC25A36), mRNA.
JD253462 - Sequence 234486 from Patent EP1572962.
JD217578 - Sequence 198602 from Patent EP1572962.
JD447970 - Sequence 428994 from Patent EP1572962.
JD438624 - Sequence 419648 from Patent EP1572962.
JD378330 - Sequence 359354 from Patent EP1572962.
JD408099 - Sequence 389123 from Patent EP1572962.
AB528573 - Synthetic construct DNA, clone: pF1KB9279, Homo sapiens SLC25A36 gene for solute carrier family 25, member 36, without stop codon, in Flexi system.
EU831411 - Synthetic construct Homo sapiens clone HAIB:100066440; DKFZo008A1017 solute carrier family 25, member 36 protein (SLC25A36) gene, encodes complete protein.
EU831504 - Synthetic construct Homo sapiens clone HAIB:100066533; DKFZo004A1018 solute carrier family 25, member 36 protein (SLC25A36) gene, encodes complete protein.
KJ894151 - Synthetic construct Homo sapiens clone ccsbBroadEn_03545 SLC25A36 gene, encodes complete protein.
JD023891 - Sequence 4915 from Patent EP1572962.
JD033018 - Sequence 14042 from Patent EP1572962.
LF378239 - JP 2014500723-A/185742: Polycomb-Associated Non-Coding RNAs.
MA613816 - JP 2018138019-A/185742: Polycomb-Associated Non-Coding RNAs.
LF378238 - JP 2014500723-A/185741: Polycomb-Associated Non-Coding RNAs.
MA613815 - JP 2018138019-A/185741: Polycomb-Associated Non-Coding RNAs.
AL049246 - Homo sapiens mRNA; cDNA DKFZp564C053 (from clone DKFZp564C053).
LF378237 - JP 2014500723-A/185740: Polycomb-Associated Non-Coding RNAs.
MA613814 - JP 2018138019-A/185740: Polycomb-Associated Non-Coding RNAs.
JD190247 - Sequence 171271 from Patent EP1572962.
JD259182 - Sequence 240206 from Patent EP1572962.
JD259066 - Sequence 240090 from Patent EP1572962.
JD285097 - Sequence 266121 from Patent EP1572962.
LF378236 - JP 2014500723-A/185739: Polycomb-Associated Non-Coding RNAs.
MA613813 - JP 2018138019-A/185739: Polycomb-Associated Non-Coding RNAs.
JD225758 - Sequence 206782 from Patent EP1572962.
JD093184 - Sequence 74208 from Patent EP1572962.
LF378235 - JP 2014500723-A/185738: Polycomb-Associated Non-Coding RNAs.
MA613812 - JP 2018138019-A/185738: Polycomb-Associated Non-Coding RNAs.
LF378234 - JP 2014500723-A/185737: Polycomb-Associated Non-Coding RNAs.
MA613811 - JP 2018138019-A/185737: Polycomb-Associated Non-Coding RNAs.
LF378233 - JP 2014500723-A/185736: Polycomb-Associated Non-Coding RNAs.
MA613810 - JP 2018138019-A/185736: Polycomb-Associated Non-Coding RNAs.
LF378232 - JP 2014500723-A/185735: Polycomb-Associated Non-Coding RNAs.
MA613809 - JP 2018138019-A/185735: Polycomb-Associated Non-Coding RNAs.
LF378231 - JP 2014500723-A/185734: Polycomb-Associated Non-Coding RNAs.
MA613808 - JP 2018138019-A/185734: Polycomb-Associated Non-Coding RNAs.
LF378230 - JP 2014500723-A/185733: Polycomb-Associated Non-Coding RNAs.
MA613807 - JP 2018138019-A/185733: Polycomb-Associated Non-Coding RNAs.
JD352627 - Sequence 333651 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A8MYF7, NM_001104647, Q05CY1, Q96CQ1, Q9H0G8, Q9NVN5, S2536_HUMAN, uc003etr.1, uc003etr.2, uc003etr.3, uc003etr.4
UCSC ID: uc003etr.4
RefSeq Accession: NM_001104647
Protein: Q96CQ1 (aka S2536_HUMAN)
CCDS: CCDS3114.1, CCDS46927.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.