Human Gene SPAG11A (ENST00000326625.5)
  Description: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. (from UniProt C9IZU7)
Gencode Transcript: ENST00000326625.5
Gencode Gene: ENSG00000178287.18
Transcript (Including UTRs)
   Position: hg38 chr8:7,859,178-7,860,982 Size: 1,805 Total Exon Count: 2 Strand: +
Coding Region
   Position: hg38 chr8:7,859,231-7,860,833 Size: 1,603 Coding Exon Count: 2 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther Names
Data last updated at UCSC: 2021-01-14 15:32:12

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr8:7,859,178-7,860,982)mRNA (may differ from genome)Protein (80 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS

-  Comments and Description Text from UniProtKB
DESCRIPTION: SubName: Full=Sperm-associated antigen 11A;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -17.1053-0.323 Picture PostScript Text
3' UTR -33.40149-0.224 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001855 - Defensin_beta-typ

Pfam Domains:
PF00711 - Beta defensin

ModBase Predicted Comparative 3D Structure on C9IZU7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Biological Process:
GO:0006952 defense response

Cellular Component:
GO:0005576 extracellular region

-  Descriptions from all associated GenBank mRNAs
  AF168617 - Homo sapiens HE2 beta1 mRNA, complete cds.
BC125141 - Homo sapiens sperm associated antigen 11B, mRNA (cDNA clone IMAGE:40119847).
BC058833 - Homo sapiens sperm associated antigen 11A, mRNA (cDNA clone MGC:61846 IMAGE:6615920), complete cds.
X67697 - H.sapiens HE2 mRNA.
AF168618 - Homo sapiens HE2 beta2 mRNA, complete cds.
KJ904340 - Synthetic construct Homo sapiens clone ccsbBroadEn_13734 SPAG11A gene, encodes complete protein.
AF170797 - Homo sapiens HE2 alpha2 mRNA, partial cds.
JD110809 - Sequence 91833 from Patent EP1572962.
JD349641 - Sequence 330665 from Patent EP1572962.
JD475165 - Sequence 456189 from Patent EP1572962.
JD349443 - Sequence 330467 from Patent EP1572962.
JD345840 - Sequence 326864 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: BC125141, C9IZU7, C9IZU7_HUMAN, ENST00000326625.1, ENST00000326625.2, ENST00000326625.3, ENST00000326625.4, uc064kbo.1
UCSC ID: ENST00000326625.5
RefSeq Accession: NM_001363726
Protein: C9IZU7

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.