Human Gene NKAPD1 (ENST00000393047.8) Description and Page Index
  Description: Homo sapiens NKAP domain containing 1 (NKAPD1), transcript variant 1, mRNA. (from RefSeq NM_018195)
Gencode Transcript: ENST00000393047.8
Gencode Gene: ENSG00000150776.18
Transcript (Including UTRs)
   Position: hg38 chr11:112,074,299-112,085,150 Size: 10,852 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg38 chr11:112,075,575-112,082,972 Size: 7,398 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2021-01-14 15:32:12

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr11:112,074,299-112,085,150)mRNA (may differ from genome)Protein (293 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDLynxMGI

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Uncharacterized protein C11orf57;
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 3.87 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 92.82 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -271.80626-0.434 Picture PostScript Text
3' UTR -580.602178-0.267 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q6ZUT1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

-  Descriptions from all associated GenBank mRNAs
  LF208480 - JP 2014500723-A/15983: Polycomb-Associated Non-Coding RNAs.
MA444057 - JP 2018138019-A/15983: Polycomb-Associated Non-Coding RNAs.
BX538107 - Homo sapiens mRNA; cDNA DKFZp686K15145 (from clone DKFZp686K15145); complete cds.
AK125340 - Homo sapiens cDNA FLJ43350 fis, clone NT2RP7004123.
AK094203 - Homo sapiens cDNA FLJ36884 fis, clone BLADE2000463.
BC048133 - Homo sapiens chromosome 11 open reading frame 57, mRNA (cDNA clone MGC:57486 IMAGE:5295844), complete cds.
BC072455 - Homo sapiens chromosome 11 open reading frame 57, mRNA (cDNA clone MGC:87956 IMAGE:6185048), complete cds.
AB096251 - Homo sapiens LOH11CR1L gene, loss of heterozygosity, 11, chromosomal region 1 gene L product.
LF208479 - JP 2014500723-A/15982: Polycomb-Associated Non-Coding RNAs.
MA444056 - JP 2018138019-A/15982: Polycomb-Associated Non-Coding RNAs.
LF376918 - JP 2014500723-A/184421: Polycomb-Associated Non-Coding RNAs.
MA612495 - JP 2018138019-A/184421: Polycomb-Associated Non-Coding RNAs.
BC030546 - Homo sapiens chromosome 11 open reading frame 57, mRNA (cDNA clone IMAGE:5166655), partial cds.
BC005403 - Homo sapiens chromosome 11 open reading frame 57, mRNA (cDNA clone IMAGE:3464389), partial cds.
CU687238 - Synthetic construct Homo sapiens gateway clone IMAGE:100022896 5' read C11orf57 mRNA.
KJ902792 - Synthetic construct Homo sapiens clone ccsbBroadEn_12186 C11orf57 gene, encodes complete protein.
AK001588 - Homo sapiens cDNA FLJ10726 fis, clone NT2RP3001216, weakly similar to CYLICIN I.
LF376916 - JP 2014500723-A/184419: Polycomb-Associated Non-Coding RNAs.
MA612493 - JP 2018138019-A/184419: Polycomb-Associated Non-Coding RNAs.
CU688898 - Synthetic construct Homo sapiens gateway clone IMAGE:100023283 5' read C11orf57 mRNA.
KJ902793 - Synthetic construct Homo sapiens clone ccsbBroadEn_12187 C11orf57 gene, encodes complete protein.
JD089080 - Sequence 70104 from Patent EP1572962.
JD552596 - Sequence 533620 from Patent EP1572962.
LF376915 - JP 2014500723-A/184418: Polycomb-Associated Non-Coding RNAs.
MA612492 - JP 2018138019-A/184418: Polycomb-Associated Non-Coding RNAs.
LF376914 - JP 2014500723-A/184417: Polycomb-Associated Non-Coding RNAs.
MA612491 - JP 2018138019-A/184417: Polycomb-Associated Non-Coding RNAs.
JD151524 - Sequence 132548 from Patent EP1572962.
JD326165 - Sequence 307189 from Patent EP1572962.
JD446322 - Sequence 427346 from Patent EP1572962.
JD444655 - Sequence 425679 from Patent EP1572962.
LF376913 - JP 2014500723-A/184416: Polycomb-Associated Non-Coding RNAs.
MA612490 - JP 2018138019-A/184416: Polycomb-Associated Non-Coding RNAs.
JD058709 - Sequence 39733 from Patent EP1572962.
JD270119 - Sequence 251143 from Patent EP1572962.
JD476456 - Sequence 457480 from Patent EP1572962.
JD053478 - Sequence 34502 from Patent EP1572962.
JD082924 - Sequence 63948 from Patent EP1572962.
JD348468 - Sequence 329492 from Patent EP1572962.
JD305106 - Sequence 286130 from Patent EP1572962.
JD363878 - Sequence 344902 from Patent EP1572962.
DQ587593 - Homo sapiens piRNA piR-54705, complete sequence.
JD268173 - Sequence 249197 from Patent EP1572962.
JD050886 - Sequence 31910 from Patent EP1572962.
JD496286 - Sequence 477310 from Patent EP1572962.
JD393839 - Sequence 374863 from Patent EP1572962.
JD487722 - Sequence 468746 from Patent EP1572962.
JD402436 - Sequence 383460 from Patent EP1572962.
JD167163 - Sequence 148187 from Patent EP1572962.
JD359459 - Sequence 340483 from Patent EP1572962.
JD296712 - Sequence 277736 from Patent EP1572962.
JD500430 - Sequence 481454 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C11orf57, CK057_HUMAN, ENST00000393047.1, ENST00000393047.2, ENST00000393047.3, ENST00000393047.4, ENST00000393047.5, ENST00000393047.6, ENST00000393047.7, NM_018195, Q5RL41, Q6IN53, Q6ZUT1, Q7Z357, Q8N2T3, uc001pmt.1, uc001pmt.2, uc001pmt.3, uc001pmt.4, uc001pmt.5, uc001pmt.6
UCSC ID: ENST00000393047.8
RefSeq Accession: NM_018195
Protein: Q6ZUT1 (aka CK057_HUMAN)
CCDS: CCDS8356.2, CCDS41715.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.