Human Gene ELAPOR2 (ENST00000450689.7)
  Description: Homo sapiens endosome-lysosome associated apoptosis and autophagy regulator family member 2 (ELAPOR2), transcript variant 1, mRNA. (from RefSeq NM_001142749)
Gencode Transcript: ENST00000450689.7
Gencode Gene: ENSG00000164659.15
Transcript (Including UTRs)
   Position: hg38 chr7:86,876,906-87,059,654 Size: 182,749 Total Exon Count: 22 Strand: -
Coding Region
   Position: hg38 chr7:86,880,471-87,059,513 Size: 179,043 Coding Exon Count: 22 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2021-01-14 15:32:12

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr7:86,876,906-87,059,654)mRNA (may differ from genome)Protein (1029 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDMGIneXtProt

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=UPF0577 protein KIAA1324-like; AltName: Full=Estrogen-induced gene 121-like protein; Short=hEIG121L; Flags: Precursor;
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).
SIMILARITY: Belongs to the UPF0577 family.
SEQUENCE CAUTION: Sequence=AAI17310.1; Type=Erroneous initiation; Sequence=BAB71041.1; Type=Frameshift; Positions=719;

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 7.88 RPKM in Brain - Spinal cord (cervical c-1)
Total median expression: 131.41 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -72.90141-0.517 Picture PostScript Text
3' UTR -882.203565-0.247 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR009030 - Growth_fac_rcpt
IPR009011 - Man6P_isomerase_rcpt-bd_dom

ModBase Predicted Comparative 3D Structure on A8MWY0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologGenome BrowserNo ortholog
Gene Details     
Gene Sorter     
MGIRGDEnsembl WormBase 
Protein SequenceProtein Sequence  Protein Sequence 
AlignmentAlignment  Alignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane

-  Descriptions from all associated GenBank mRNAs
  AK055902 - Homo sapiens cDNA FLJ31340 fis, clone MESAN1000035, weakly similar to MAJOR SURFACE-LABELED TROPHOZOITE ANTIGEN PRECURSOR.
AK303619 - Homo sapiens cDNA FLJ59650 complete cds.
AK296250 - Homo sapiens cDNA FLJ56377 complete cds.
BC117309 - Homo sapiens KIAA1324-like, mRNA (cDNA clone MGC:150918 IMAGE:40125860), complete cds.
HQ258658 - Synthetic construct Homo sapiens clone IMAGE:100072688 Unknown protein gene, encodes complete protein.
KJ904039 - Synthetic construct Homo sapiens clone ccsbBroadEn_13433 KIAA1324L gene, encodes complete protein.
JD040745 - Sequence 21769 from Patent EP1572962.
JD530204 - Sequence 511228 from Patent EP1572962.
JD309376 - Sequence 290400 from Patent EP1572962.
JD429678 - Sequence 410702 from Patent EP1572962.
JD042353 - Sequence 23377 from Patent EP1572962.
JD173821 - Sequence 154845 from Patent EP1572962.
JD329968 - Sequence 310992 from Patent EP1572962.
JD043495 - Sequence 24519 from Patent EP1572962.
JD073329 - Sequence 54353 from Patent EP1572962.
JD378502 - Sequence 359526 from Patent EP1572962.
JD347507 - Sequence 328531 from Patent EP1572962.
JD419099 - Sequence 400123 from Patent EP1572962.
JD273119 - Sequence 254143 from Patent EP1572962.
JD419753 - Sequence 400777 from Patent EP1572962.
JD561056 - Sequence 542080 from Patent EP1572962.
JD501199 - Sequence 482223 from Patent EP1572962.
JD539490 - Sequence 520514 from Patent EP1572962.
JD039372 - Sequence 20396 from Patent EP1572962.
JD090837 - Sequence 71861 from Patent EP1572962.
JD251420 - Sequence 232444 from Patent EP1572962.
JD263632 - Sequence 244656 from Patent EP1572962.
JD346122 - Sequence 327146 from Patent EP1572962.
JD088808 - Sequence 69832 from Patent EP1572962.
JD152879 - Sequence 133903 from Patent EP1572962.
JD418916 - Sequence 399940 from Patent EP1572962.
JD553470 - Sequence 534494 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A4D1C9, A8MWY0, B4DJV3, EIG121L, ENST00000450689.1, ENST00000450689.2, ENST00000450689.3, ENST00000450689.4, ENST00000450689.5, ENST00000450689.6, K132L_HUMAN, KIAA1324L, NM_001142749, Q17RI6, Q96DP2, uc011kha.1, uc011kha.2, uc011kha.3, uc011kha.4, uc011kha.5
UCSC ID: ENST00000450689.7
RefSeq Accession: NM_001142749
Protein: A8MWY0 (aka K132L_HUMAN)
CCDS: CCDS47632.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.