Human Gene MIR4689 (ENST00000582517.1) from GENCODE V44
  Description: Homo sapiens microRNA 4689 (MIR4689), microRNA. (from RefSeq NR_039838)
RefSeq Summary (NR_039838): microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage.
Gencode Transcript: ENST00000582517.1
Gencode Gene: ENSG00000264101.1
Transcript (Including UTRs)
   Position: hg38 chr1:5,862,672-5,862,741 Size: 70 Total Exon Count: 1 Strand: -


Page IndexSequence and LinksPrimersRNA-Seq ExpressionMicroarray ExpressionOther Species
mRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2023-08-18 00:09:47

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:5,862,672-5,862,741)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGencodeHGNCLynxPubMed

-  Primer design for this transcript
 

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Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.00 RPKM in Adipose - Subcutaneous
Total median expression: 0.00 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  HZ409494 - JP 2015528002-A/2091: CHIRAL CONTROL.
HZ459701 - WO 2015182781-A/404: Kit or device and method for detecting pancreatic cancer.
HZ460800 - WO 2015190584-A/297: Kit or device and method for detecting prostate cancer.
HZ461514 - WO 2015190586-A/327: Kit and method for detecting colon cancer.
HZ462235 - WO 2015190591-A/390: Kit and method for detecting breast cancer.
HZ463291 - WO 2015194535-A/385: Kit and method for detecting stomach cancer.
HZ463890 - WO 2015194610-A/326: Kit and method for detecting lung cancer.
HZ465340 - WO 2015194627-A/393: Kit and method for detecting esophageal cancer.
LG052828 - KR 1020150036642-A/2094: CHIRAL CONTROL.
LY481141 - KR 1020170010856-A/404: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LY496523 - KR 1020170018406-A/393: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497157 - KR 1020170016485-A/327: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497791 - KR 1020170018409-A/326: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY499238 - KR 1020170018412-A/390: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500104 - KR 1020170019425-A/385: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500673 - KR 1020170016490-A/297: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238686 - WO 2017171048-A/347: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869592 - Sequence 297 from Patent EP3156483.
MS880553 - Sequence 390 from Patent EP3156498.
MS884344 - Sequence 327 from Patent EP3156499.
MS885223 - Sequence 385 from Patent EP3156503.
MS994531 - Sequence 393 from Patent EP3159406.
MS996857 - Sequence 326 from Patent EP3159416.
FR772946 - Homo sapiens microRNA hsa-miR-4689-5p.
HW798953 - WO 2014192907-A/59: Method for detecting miRNA used for differentiating disorders causing motor neuropathy.
HW906936 - WO 2015037656-A/151: Autophagy-regulating microRNA.
HZ376553 - WO 2015133522-A/1: Theraqpeutic agent for colorectal cancer and prediction method of colorectal cancer prognosis.
HZ459666 - WO 2015182781-A/369: Kit or device and method for detecting pancreatic cancer.
HZ460614 - WO 2015190584-A/111: Kit or device and method for detecting prostate cancer.
HZ461322 - WO 2015190586-A/135: Kit and method for detecting colon cancer.
HZ461958 - WO 2015190591-A/113: Kit and method for detecting breast cancer.
HZ463093 - WO 2015194535-A/187: Kit and method for detecting stomach cancer.
HZ463710 - WO 2015194610-A/146: Kit and method for detecting lung cancer.
HZ465130 - WO 2015194627-A/183: Kit and method for detecting esophageal cancer.
HZ481823 - JP 2015535430-A/2329: TERMINALLY MODIFIED RNA.
HZ791754 - JP 2016504050-A/3499: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC514486 - Sequence 4739 from Patent WO2014113089.
LF160224 - JP 2016513950-A/290: Oligomers with improved off-target profile.
LQ072074 - Sequence 2398 from Patent EP2964234.
LQ724746 - Sequence 379 from Patent WO2018096084.
LY481106 - KR 1020170010856-A/369: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LY496313 - KR 1020170018406-A/183: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY496965 - KR 1020170016485-A/135: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497611 - KR 1020170018409-A/146: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY498961 - KR 1020170018412-A/113: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY499906 - KR 1020170019425-A/187: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500487 - KR 1020170016490-A/111: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238433 - WO 2017171048-A/94: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MA406155 - WO 2018155427-A/929: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MA645575 - JP 2017113010-A/3499: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA733459 - JP 2017140048-A/2329: TERMINALLY MODIFIED RNA.
MS869406 - Sequence 111 from Patent EP3156483.
MS880276 - Sequence 113 from Patent EP3156498.
MS884152 - Sequence 135 from Patent EP3156499.
MS885025 - Sequence 187 from Patent EP3156503.
MS994321 - Sequence 183 from Patent EP3159406.
MS996677 - Sequence 146 from Patent EP3159416.
HZ459741 - WO 2015182781-A/444: Kit or device and method for detecting pancreatic cancer.
HZ461001 - WO 2015190584-A/498: Kit or device and method for detecting prostate cancer.
HZ461725 - WO 2015190586-A/538: Kit and method for detecting colon cancer.
HZ462518 - WO 2015190591-A/673: Kit and method for detecting breast cancer.
HZ463521 - WO 2015194535-A/615: Kit and method for detecting stomach cancer.
HZ464083 - WO 2015194610-A/519: Kit and method for detecting lung cancer.
HZ465569 - WO 2015194627-A/622: Kit and method for detecting esophageal cancer.
LY481181 - KR 1020170010856-A/444: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD.
LY496752 - KR 1020170018406-A/622: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497368 - KR 1020170016485-A/538: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497984 - KR 1020170018409-A/519: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY499521 - KR 1020170018412-A/673: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500334 - KR 1020170019425-A/615: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY500874 - KR 1020170016490-A/498: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238962 - WO 2017171048-A/623: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869793 - Sequence 498 from Patent EP3156483.
MS880836 - Sequence 673 from Patent EP3156498.
MS884555 - Sequence 538 from Patent EP3156499.
MS885453 - Sequence 615 from Patent EP3156503.
MS994760 - Sequence 622 from Patent EP3159406.
MS997050 - Sequence 519 from Patent EP3159416.
MA822761 - WO 2019004436-A/574: Kit, device, and method for detection of lung cancer.
MA822424 - WO 2019004436-A/237: Kit, device, and method for detection of lung cancer.
MA823101 - WO 2019004436-A/914: Kit, device, and method for detection of lung cancer.
MA806088 - WO 2018199275-A/348: Kit, device and method for detection of ovary tumor.
MA802628 - JP 2018183181-A/3499: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA805810 - WO 2018199275-A/70: Kit, device and method for detection of ovary tumor.
MA806354 - WO 2018199275-A/614: Kit, device and method for detection of ovary tumor.
LY616450 - KR 1020180129785-A/347: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
LY616197 - KR 1020180129785-A/94: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
LY616726 - KR 1020180129785-A/623: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.

-  Other Names for This Gene
  Alternate Gene Symbols: NR_039838, uc021ofn.1
UCSC ID: ENST00000582517.1
RefSeq Accession: NR_039838

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.