Human Gene GPRIN3 (ENST00000609438.2) Description and Page Index
  Description: Homo sapiens GPRIN family member 3 (GPRIN3), mRNA. (from RefSeq NM_198281)
Gencode Transcript: ENST00000609438.2
Gencode Gene: ENSG00000185477.5
Transcript (Including UTRs)
   Position: hg38 chr4:89,236,383-89,307,800 Size: 71,418 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg38 chr4:89,247,780-89,250,110 Size: 2,331 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2021-01-14 15:32:12

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:89,236,383-89,307,800)mRNA (may differ from genome)Protein (776 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSCGAP
EnsemblEntrez GeneExonPrimerGeneCardsHGNCHPRD
LynxMGIneXtProtOMIMPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: GRIN3_HUMAN
DESCRIPTION: RecName: Full=G protein-regulated inducer of neurite outgrowth 3; Short=GRIN3;
FUNCTION: May be involved in neurite outgrowth (By similarity).
SEQUENCE CAUTION: Sequence=BAC23123.2; Type=Erroneous initiation;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 9.21 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 67.22 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -129.70309-0.420 Picture PostScript Text
3' UTR -2831.3411397-0.248 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026646 - GPRIN2-like/GPRIN3

ModBase Predicted Comparative 3D Structure on Q6ZVF9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
MGIRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  AK124616 - Homo sapiens cDNA FLJ42625 fis, clone BRACE3016884.
JD412693 - Sequence 393717 from Patent EP1572962.
JD324174 - Sequence 305198 from Patent EP1572962.
JD197748 - Sequence 178772 from Patent EP1572962.
JD173957 - Sequence 154981 from Patent EP1572962.
JD412692 - Sequence 393716 from Patent EP1572962.
JD197747 - Sequence 178771 from Patent EP1572962.
JD212356 - Sequence 193380 from Patent EP1572962.
JD212355 - Sequence 193379 from Patent EP1572962.
JD412690 - Sequence 393714 from Patent EP1572962.
JD100892 - Sequence 81916 from Patent EP1572962.
JD538325 - Sequence 519349 from Patent EP1572962.
JD283344 - Sequence 264368 from Patent EP1572962.
JD212354 - Sequence 193378 from Patent EP1572962.
JD375992 - Sequence 357016 from Patent EP1572962.
JD222859 - Sequence 203883 from Patent EP1572962.
AK057653 - Homo sapiens cDNA FLJ33091 fis, clone TRACH2000660.
AK026379 - Homo sapiens cDNA: FLJ22726 fis, clone HSI15005.
AK091461 - Homo sapiens cDNA FLJ34142 fis, clone FCBBF3011523.
AX746998 - Sequence 523 from Patent EP1308459.
AB095947 - Homo sapiens mRNA for KIAA2027 protein.
JD165626 - Sequence 146650 from Patent EP1572962.
JD286471 - Sequence 267495 from Patent EP1572962.
JD496266 - Sequence 477290 from Patent EP1572962.
JD262981 - Sequence 244005 from Patent EP1572962.
JD224152 - Sequence 205176 from Patent EP1572962.
JD416578 - Sequence 397602 from Patent EP1572962.
JD375013 - Sequence 356037 from Patent EP1572962.
BC126371 - Homo sapiens GPRIN family member 3, mRNA (cDNA clone MGC:161649 IMAGE:8992087), complete cds.
HQ258503 - Synthetic construct Homo sapiens clone IMAGE:100072932 GPRIN family member 3 (GPRIN3) gene, encodes complete protein.
KJ900587 - Synthetic construct Homo sapiens clone ccsbBroadEn_09981 GPRIN3 gene, encodes complete protein.
AB527401 - Synthetic construct DNA, clone: pF1KA2027, Homo sapiens GPRIN3 gene for GPRIN family member 3, without stop codon, in Flexi system.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000609438.1, GRIN3_HUMAN, KIAA2027, NM_198281, Q6ZVF9, Q8IVE4, uc003hsm.1, uc003hsm.2, uc003hsm.3
UCSC ID: ENST00000609438.2
RefSeq Accession: NM_198281
Protein: Q6ZVF9 (aka GRIN3_HUMAN)
CCDS: CCDS34030.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.