Human Gene RBIS (ENST00000612809.4) Description and Page Index
  Description: Homo sapiens ribosomal biogenesis factor (RBIS), transcript variant 3, mRNA. (from RefSeq NM_001099672)
Gencode Transcript: ENST00000612809.4
Gencode Gene: ENSG00000176731.12
Transcript (Including UTRs)
   Position: hg38 chr8:85,214,502-85,220,375 Size: 5,874 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg38 chr8:85,214,560-85,217,499 Size: 2,940 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr8:85,214,502-85,220,375)mRNA (may differ from genome)Protein (100 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDMGIneXtProt
PubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Uncharacterized protein C8orf59;

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 25.63 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 610.15 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -25.80114-0.226 Picture PostScript Text
3' UTR -3.5058-0.060 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8N0T1
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  BC055092 - Homo sapiens cDNA clone IMAGE:4737427.
BC146983 - Homo sapiens chromosome 8 open reading frame 59, mRNA (cDNA clone MGC:182086 IMAGE:9056911), complete cds.
BC146988 - Homo sapiens chromosome 8 open reading frame 59, mRNA (cDNA clone MGC:182091 IMAGE:9056916), complete cds.
BC157825 - Homo sapiens chromosome 8 open reading frame 59, mRNA (cDNA clone MGC:189720 IMAGE:9057044), complete cds.
BC171873 - Homo sapiens cDNA clone IMAGE:9054527.
AK000414 - Homo sapiens cDNA FLJ20407 fis, clone KAT01658.
BC062221 - Homo sapiens cDNA clone IMAGE:6385427.
JD411101 - Sequence 392125 from Patent EP1572962.
BC032347 - Homo sapiens chromosome 8 open reading frame 59, mRNA (cDNA clone IMAGE:5212747), complete cds.
KJ904279 - Synthetic construct Homo sapiens clone ccsbBroadEn_13673 C8orf59 gene, encodes complete protein.
JD241621 - Sequence 222645 from Patent EP1572962.
JD551456 - Sequence 532480 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B2RXE7, C8orf59, CH059_HUMAN, NM_001099672, Q8N0T1, uc033brv.1, uc033brv.2
UCSC ID: uc033brv.2
RefSeq Accession: NM_001099672
Protein: Q8N0T1 (aka CH059_HUMAN)
CCDS: CCDS55255.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.