Human Gene PSD3 (ENST00000614430.3) Description and Page Index
  Description: pleckstrin and Sec7 domain containing 3 (from HGNC PSD3)
Gencode Transcript: ENST00000614430.3
Gencode Gene: ENSG00000156011.17
Transcript (Including UTRs)
   Position: hg38 chr8:18,530,561-18,684,076 Size: 153,516 Total Exon Count: 6 Strand: -
Coding Region
   Position: hg38 chr8:18,535,743-18,683,932 Size: 148,190 Coding Exon Count: 6 

Page IndexSequence and LinksCTDRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Other SpeciesmRNA DescriptionsPathwaysOther NamesMethods
Data last updated at UCSC: 2021-01-14 15:32:12

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr8:18,530,561-18,684,076)mRNA (may differ from genome)Protein (269 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaBioGPS

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • D013749 Tetrachlorodibenzodioxin
  • D000082 Acetaminophen
  • D001564 Benzo(a)pyrene
  • C517041 (4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)
  • C111118 2',3,3',4',5-pentachloro-4-hydroxybiphenyl
  • C014024 2,4,5,2',4',5'-hexachlorobiphenyl
  • C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
  • D000535 Aluminum
  • D002945 Cisplatin
          more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 47.27 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 323.96 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -36.70144-0.255 Picture PostScript Text
3' UTR -1407.105182-0.272 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein SequenceProtein Sequence    

-  Descriptions from all associated GenBank mRNAs
  AL832778 - Homo sapiens mRNA; cDNA DKFZp686G087 (from clone DKFZp686G087).
AK091317 - Homo sapiens cDNA FLJ33998 fis, clone FCBBF1000023, moderately similar to Mus musculus pleckstrin and Sec7 domain containing 3 (Psd3), transcript variant 2, mRNA.
AX746913 - Sequence 438 from Patent EP1308459.
GU727648 - Homo sapiens epididymis tissue sperm binding protein Li 20mP mRNA, complete cds.
BX647320 - Homo sapiens mRNA; cDNA DKFZp686A1849 (from clone DKFZp686A1849).
AF243495 - Homo sapiens hepatocellular carcinoma-associated antigen 67 (HCA67) mRNA, complete cds.
AB023159 - Homo sapiens KIAA0942 mRNA for KIAA0942 protein.
BX647406 - Homo sapiens mRNA; cDNA DKFZp686E1349 (from clone DKFZp686E1349).
AK296546 - Homo sapiens cDNA FLJ54694 complete cds, highly similar to Pleckstrin and Sec7 domain-containing protein3.
BC045112 - Homo sapiens pleckstrin and Sec7 domain containing 3, mRNA (cDNA clone IMAGE:5171384), with apparent retained intron.
BC075044 - Homo sapiens pleckstrin and Sec7 domain containing 3, mRNA (cDNA clone MGC:104121 IMAGE:30915575), complete cds.
BC075045 - Homo sapiens pleckstrin and Sec7 domain containing 3, mRNA (cDNA clone MGC:103960 IMAGE:30915359), complete cds.
EU832237 - Synthetic construct Homo sapiens clone HAIB:100067266; DKFZo004E1026 pleckstrin and Sec7 domain containing 3 protein (PSD3) gene, encodes complete protein.
EU832242 - Synthetic construct Homo sapiens clone HAIB:100067271; DKFZo004F0326 pleckstrin and Sec7 domain containing 3 protein (PSD3) gene, encodes complete protein.
AF519767 - Homo sapiens ADP-ribosylation factor guanine nucleotide factor 6 mRNA, complete cds.
AK315099 - Homo sapiens cDNA, FLJ96057.
EU832144 - Synthetic construct Homo sapiens clone HAIB:100067173; DKFZo008E1025 pleckstrin and Sec7 domain containing 3 protein (PSD3) gene, encodes complete protein.
EU832149 - Synthetic construct Homo sapiens clone HAIB:100067178; DKFZo008F0325 pleckstrin and Sec7 domain containing 3 protein (PSD3) gene, encodes complete protein.
AB463178 - Synthetic construct DNA, clone: pF1KA0942, Homo sapiens PSD3 gene for pleckstrin and Sec7 domain containing 3, without stop codon, in Flexi system.
JD567081 - Sequence 548105 from Patent EP1572962.
JD110831 - Sequence 91855 from Patent EP1572962.
JD061749 - Sequence 42773 from Patent EP1572962.
JD368118 - Sequence 349142 from Patent EP1572962.
JD073246 - Sequence 54270 from Patent EP1572962.
JD188161 - Sequence 169185 from Patent EP1572962.
JD179173 - Sequence 160197 from Patent EP1572962.
JD526911 - Sequence 507935 from Patent EP1572962.
JD506385 - Sequence 487409 from Patent EP1572962.
JD260295 - Sequence 241319 from Patent EP1572962.
JD052612 - Sequence 33636 from Patent EP1572962.
JD262444 - Sequence 243468 from Patent EP1572962.
JD180646 - Sequence 161670 from Patent EP1572962.
JD228012 - Sequence 209036 from Patent EP1572962.
JD509070 - Sequence 490094 from Patent EP1572962.
JD113676 - Sequence 94700 from Patent EP1572962.
JD548444 - Sequence 529468 from Patent EP1572962.
JD161134 - Sequence 142158 from Patent EP1572962.
JD099660 - Sequence 80684 from Patent EP1572962.
JD433458 - Sequence 414482 from Patent EP1572962.
JD433311 - Sequence 414335 from Patent EP1572962.
JD559120 - Sequence 540144 from Patent EP1572962.
JD147108 - Sequence 128132 from Patent EP1572962.
JD250896 - Sequence 231920 from Patent EP1572962.
JD059155 - Sequence 40179 from Patent EP1572962.
JD480870 - Sequence 461894 from Patent EP1572962.
JD330482 - Sequence 311506 from Patent EP1572962.
JD566773 - Sequence 547797 from Patent EP1572962.
JD263664 - Sequence 244688 from Patent EP1572962.
JD245407 - Sequence 226431 from Patent EP1572962.
JD381794 - Sequence 362818 from Patent EP1572962.
JD521683 - Sequence 502707 from Patent EP1572962.
JD262405 - Sequence 243429 from Patent EP1572962.
JD261586 - Sequence 242610 from Patent EP1572962.
JD325526 - Sequence 306550 from Patent EP1572962.
JD073998 - Sequence 55022 from Patent EP1572962.
JD309426 - Sequence 290450 from Patent EP1572962.
JD142898 - Sequence 123922 from Patent EP1572962.
JD491825 - Sequence 472849 from Patent EP1572962.
JD548699 - Sequence 529723 from Patent EP1572962.
JD063255 - Sequence 44279 from Patent EP1572962.
JD261133 - Sequence 242157 from Patent EP1572962.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa04144 - Endocytosis

-  Other Names for This Gene
  Alternate Gene Symbols: A0A087WXD8, BX647320, ENST00000614430.1, ENST00000614430.2, uc064kqy.1
UCSC ID: ENST00000614430.3
RefSeq Accession: NM_206909

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.