Mouse Gene Supt3h (R6240) Description and Page Index
  Description: suppressor of Ty 3 homolog
Transcript (Including UTRs)
   Position: mm8 chr17:44,240,226-44,582,865 Size: 342,640 Total Exon Count: 12 Strand: +
Coding Region
   Position: mm8 chr17:44,249,665-44,582,765 Size: 333,101 Coding Exon Count: 11 

Page IndexSequence and LinksCTDMicroarray ExpressionRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2006-02-27

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr17:44,240,226-44,582,865)mRNA (may differ from genome)Protein (374 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAllen Brain Atlas
BioGPSCGAPEnsemblEntrez GeneGeneCardsGeneNetwork
MGIPubMedStanford SOURCEUniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
Expression ratio colors:

GNF Expression Atlas Data from U74b Mouse Chip


Affymetrix All Exon Microarrays


-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -59.50258-0.231 Picture PostScript Text
3' UTR -26.00100-0.260 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR009072 - Histone-fold
IPR003195 - TFIID-18

Pfam Domains:
PF02269 - Transcription initiation factor IID, 18kD subunit

ModBase Predicted Comparative 3D Structure on Q8BVY4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologGenome BrowserGenome BrowserNo orthologGenome Browser
Gene Details  Gene Details Gene Details
Gene Sorter  Gene Sorter Gene Sorter
GenBank EnsemblFlyBase SGD
Protein Sequence Protein SequenceProtein Sequence Protein Sequence
Alignment AlignmentAlignment Alignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0046982 protein heterodimerization activity

Biological Process:
GO:0006366 transcription from RNA polymerase II promoter
GO:0016578 histone deubiquitination
GO:0043966 histone H3 acetylation

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0030914 STAGA complex
GO:0033276 transcription factor TFTC complex

-  Descriptions from all associated GenBank mRNAs
  AK075916 - Mus musculus adult male tongue cDNA, RIKEN full-length enriched library, clone:2310066G22 product:similar to TRANSCRIPTION FACTOR SUPT3H [Homo sapiens], full insert sequence.
AK089837 - Mus musculus activated spleen cDNA, RIKEN full-length enriched library, clone:F830031F15 product:suppressor of Ty 3 homolog (S. cerevisiae), full insert sequence.
AK087935 - Mus musculus 2 days neonate thymus thymic cells cDNA, RIKEN full-length enriched library, clone:E430001D11 product:similar to SPT3-LIKE PROTEIN [Homo sapiens], full insert sequence.
AK050321 - Mus musculus adult male liver tumor cDNA, RIKEN full-length enriched library, clone:C730037C19 product:similar to TRANSCRIPTION FACTOR SUPT3H [Homo sapiens], full insert sequence.
BC096051 - Mus musculus suppressor of Ty 3 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:5121973).
BC051540 - Mus musculus suppressor of Ty 3 homolog (S. cerevisiae), mRNA (cDNA clone IMAGE:5057724), containing frame-shift errors.
LF204734 - JP 2014500723-A/12237: Polycomb-Associated Non-Coding RNAs.
BC032054 - Mus musculus, clone IMAGE:3599124, mRNA.
MA440311 - JP 2018138019-A/12237: Polycomb-Associated Non-Coding RNAs.
AK148564 - Mus musculus 2 days neonate sympathetic ganglion cDNA, RIKEN full-length enriched library, clone:7120408C19 product:suppressor of Ty 3 homolog (S. cerevisiae), full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: AK050321, AK075916, AK087935, SPT3, SPT3L
UCSC ID: NM_178652
RefSeq Accession: NM_178652
Protein: Q8BVY4

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.