S. cerevisiae Gene RTC3 (YHR087W) Description and Page Index
  Description: Protein of unknown function involved in RNA metabolism has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1) null mutation suppresses cdc13-1 temperature sensitivity
Transcript (Including UTRs)
   Position: sacCer3 chrVIII:280,820-281,155 Size: 336 Total Exon Count: 1 Strand: +
Coding Region
   Position: sacCer3 chrVIII:280,820-281,155 Size: 336 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther SpeciesGO Annotations
Other NamesMethods
Data last updated at UCSC: 2011-08-29

-  Sequence and Links to Tools and Databases
Genomic Sequence (chrVIII:280,820-281,155)mRNAProtein (111 aa)
Gene SorterGenome BrowserOther Species FASTASGDUniProtKB

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=Restriction of telomere capping protein 3;
FUNCTION: May play a role in RNA metabolism, rRNA-processing, and in a process influencing telomere capping.
MISCELLANEOUS: Present with 2430 molecules/cell in log phase SD medium.
SIMILARITY: Belongs to the SDO1-like family.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR019783 - Ribosome_mat_SBDS_N

Pfam Domains:
PF01172 - Shwachman-Bodian-Diamond syndrome (SBDS) protein

Protein Data Bank (PDB) 3-D Structure
MuPIT help


ModBase Predicted Comparative 3D Structure on P38804
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanMouseRatZebrafishD. melanogasterC. elegans
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function
GO:0003723 RNA binding

Biological Process:
GO:0006364 rRNA processing
GO:0016070 RNA metabolic process
GO:0042254 ribosome biogenesis

Cellular Component:
GO:0005634 nucleus
GO:0005737 cytoplasm

-  Other Names for This Gene
Protein: P38804 (aka SDO1L_YEAST)

-  SGD Genes Methods, Credits, and Data Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.