Mouse Gene Per1 (ENSMUST00000101004.8) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
Description: Per1 (from geneSymbol) RefSeq Summary (NM_001159367): This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene may increase the risk of getting certain cancers. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2014]. Gencode Transcript: ENSMUST00000101004.8 Gencode Gene: ENSMUSG00000020893.17 Transcript (Including UTRs) Position: mm10 chr11:69,095,217-69,106,458 Size: 11,242 Total Exon Count: 18 Strand: + Coding Region Position: mm10 chr11:69,100,642-69,105,655 Size: 5,014 Coding Exon Count: 17
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8C4K7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.