Mouse Gene Macf1 (uc008upt.1) Description and Page Index
  Description: SubName: Full=Putative uncharacterized protein;
Transcript (Including UTRs)
   Position: mm9 chr4:123,216,123-123,241,916 Size: 25,794 Total Exon Count: 4 Strand: -
Coding Region
   Position: mm9 chr4:123,217,009-123,241,772 Size: 24,764 Coding Exon Count: 4 

Page IndexSequence and LinksCTDMicroarray ExpressionRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2011-03-02

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr4:123,216,123-123,241,916)mRNA (may differ from genome)Protein (108 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblExonPrimerGeneCardsPubMedStanford SOURCE

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
Expression ratio colors:

GNF Expression Atlas 2 Data from GNF1M Mouse Chip


Affymetrix All Exon Microarrays


-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -46.86144-0.325 Picture PostScript Text
3' UTR -270.20886-0.305 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001589 - Actinin_actin-bd_CS
IPR001715 - CH-domain

Pfam Domains:
PF00307 - Calponin homology (CH) domain

SCOP Domains:
47576 - Calponin-homology domain, CH-domain

ModBase Predicted Comparative 3D Structure on Q8C221
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
Protein Sequence     

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003779 actin binding

-  Descriptions from all associated GenBank mRNAs
  AF150755 - Mus musculus microtubule-actin crosslinking factor (Macf) mRNA, complete cds.
DQ067088 - Mus musculus microtubule-actin crosslinking factor 1b mRNA, complete cds.
U67203 - Mus musculus ACF7 neural isoform 1 (mACF7) mRNA, partial cds.
U67204 - Mus musculus ACF7 neural isoform 2 (mACF7) mRNA, partial cds.
AK143540 - Mus musculus 12 days embryo whole body cDNA, RIKEN full-length enriched library, clone:E970019C21 product:microtubule-actin crosslinking factor 1, full insert sequence.
AK089453 - Mus musculus B6-derived CD11 +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F730032J06 product:hypothetical Calponin-like actin-binding/Calponin homology domain profile/Actin-binding, actinin-type containing protein, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: AK089453, Q8C221, Q8C221_MOUSE
UCSC ID: uc008upt.1
RefSeq Accession: NM_001199137
Protein: Q8C221

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: AK089453.1
exon count: 4CDS single in 3' UTR: no RNA size: 1358
ORF size: 327CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 853.50frame shift in genome: no % Coverage: 99.85
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 916# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.