ID:IQEC3_MOUSE DESCRIPTION: RecName: Full=IQ motif and SEC7 domain-containing protein 3; FUNCTION: Acts as a guanine nucleotide exchange factor (GEF) for ARF1 (By similarity). SUBUNIT: Interacts with DLG1 and DLG4 (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). TISSUE SPECIFICITY: Expressed specifically in the adult brain, but not in the fetal brain at 14 dpc. SIMILARITY: Belongs to the BRAG family. SIMILARITY: Contains 1 IQ domain. SIMILARITY: Contains 1 PH domain. SIMILARITY: Contains 1 SEC7 domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q3TES0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0030036 actin cytoskeleton organization GO:0032012 regulation of ARF protein signal transduction GO:0051056 regulation of small GTPase mediated signal transduction GO:0090630 activation of GTPase activity