Mouse Gene Dnpep (uc011wnp.1) Description and Page Index
  Description: aspartyl aminopeptidase isoform a
Transcript (Including UTRs)
   Position: mm9 chr1:75,305,140-75,314,212 Size: 9,073 Total Exon Count: 15 Strand: -
Coding Region
   Position: mm9 chr1:75,305,234-75,313,915 Size: 8,682 Coding Exon Count: 15 

Page IndexSequence and LinksUniProtKB CommentsCTDMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2011-03-02

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:75,305,140-75,314,212)mRNA (may differ from genome)Protein (475 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAllen Brain Atlas
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
MGIPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: Q3TVK3_MOUSE
DESCRIPTION: SubName: Full=Putative uncharacterized protein;
SIMILARITY: Belongs to the peptidase M18 family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

Rinn et. al Sex Gene Expression Data on MOE430A Chip

        
Ratios
        
Absolute

GNF Expression Atlas Data from U74a Mouse Chip

        
     
    
    
    
   
    
Ratios
        
     
    
    
    
   
    
Absolute
    
     
    
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Absolute

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -138.00297-0.465 Picture PostScript Text
3' UTR -24.9094-0.265 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001948 - Peptidase_M18
IPR023358 - Peptidase_M18_dom2

Pfam Domains:
PF02127 - Aminopeptidase I zinc metalloprotease (M18)

SCOP Domains:
53187 - Zn-dependent exopeptidases

ModBase Predicted Comparative 3D Structure on Q3TVK3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserGenome BrowserNo orthologGenome BrowserGenome Browser
Gene DetailsGene Details  Gene DetailsGene Details
Gene SorterGene Sorter  Gene SorterGene Sorter
GenBankRGDEnsembl WormBaseSGD
Protein SequenceProtein SequenceProtein Sequence Protein SequenceProtein Sequence
AlignmentAlignmentAlignment AlignmentAlignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0004177 aminopeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

Biological Process:
GO:0006508 proteolysis

Cellular Component:
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  AK038646 - Mus musculus adult male hypothalamus cDNA, RIKEN full-length enriched library, clone:A230052F13 product:aspartyl aminopeptidase, full insert sequence.
AK052001 - Mus musculus 12 days embryo eyeball cDNA, RIKEN full-length enriched library, clone:D230033J10 product:aspartyl aminopeptidase, full insert sequence.
AK209838 - Mus musculus cDNA, clone:Y2G0116H11, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027410, based on BLAT search.
AK213377 - Mus musculus cDNA, clone:Y2G0128C12, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027410, based on BLAT search.
BC092232 - Mus musculus aspartyl aminopeptidase, mRNA (cDNA clone MGC:116669 IMAGE:30551654), complete cds.
AF005051 - Mus musculus aspartyl aminopeptidase mRNA, complete cds.
AK166276 - Mus musculus mammary gland RCB-0526 Jyg-MC(A) cDNA, RIKEN full-length enriched library, clone:G830029N23 product:aspartyl aminopeptidase, full insert sequence.
AK160084 - Mus musculus osteoclast-like cell cDNA, RIKEN full-length enriched library, clone:I420048F09 product:aspartyl aminopeptidase, full insert sequence.
AK154744 - Mus musculus NOD-derived CD11c +ve dendritic cells cDNA, RIKEN full-length enriched library, clone:F630105G01 product:aspartyl aminopeptidase, full insert sequence.
AK182509 - Mus musculus cDNA, clone:Y0G0122I21, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK188773 - Mus musculus cDNA, clone:Y0G0146G22, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK182346 - Mus musculus cDNA, clone:Y0G0121K17, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK208235 - Mus musculus cDNA, clone:Y2G0110I11, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK208494 - Mus musculus cDNA, clone:Y2G0111J09, strand:unspecified.
AK215853 - Mus musculus cDNA, clone:Y2G0136G06, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK179297 - Mus musculus cDNA, clone:Y0G0109N01, strand:plus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK182360 - Mus musculus cDNA, clone:Y0G0121L08, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000066668, based on BLAT search.
AK188536 - Mus musculus cDNA, clone:Y0G0145J08, strand:minus, reference:ENSEMBL:Mouse-Transcript-ENST:ENSMUST00000027410, based on BLAT search.
LF216587 - JP 2014500723-A/24090: Polycomb-Associated Non-Coding RNAs.
LF216589 - JP 2014500723-A/24092: Polycomb-Associated Non-Coding RNAs.
LF216590 - JP 2014500723-A/24093: Polycomb-Associated Non-Coding RNAs.
LF192729 - JP 2014500723-A/232: Polycomb-Associated Non-Coding RNAs.
MA428306 - JP 2018138019-A/232: Polycomb-Associated Non-Coding RNAs.
MA452164 - JP 2018138019-A/24090: Polycomb-Associated Non-Coding RNAs.
MA452166 - JP 2018138019-A/24092: Polycomb-Associated Non-Coding RNAs.
MA452167 - JP 2018138019-A/24093: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001110831, NP_001104301, Q3TVK3, Q3TVK3_MOUSE, uc007bov.1
UCSC ID: uc011wnp.1
RefSeq Accession: NM_001110831
Protein: Q3TVK3 CCDS: CCDS15070.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001110831.1
exon count: 15CDS single in 3' UTR: no RNA size: 1930
ORF size: 1428CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3056.00frame shift in genome: no % Coverage: 94.25
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.