Human Gene SAXO1 (ENST00000380534.9) Description and Page Index
  Description: Homo sapiens stabilizer of axonemal microtubules 1 (SAXO1), transcript variant 1, mRNA. (from RefSeq NM_153707)
Gencode Transcript: ENST00000380534.9
Gencode Gene: ENSG00000155875.15
Transcript (Including UTRs)
   Position: hg38 chr9:18,927,650-19,033,209 Size: 105,560 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg38 chr9:18,928,052-19,032,908 Size: 104,857 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated: 2019-09-04

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:18,927,650-19,033,209)mRNA (may differ from genome)Protein (474 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
Entrez GeneExonPrimerGeneCardsHPRDLynxMGI
neXtProtOMIMPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: F154A_HUMAN
DESCRIPTION: RecName: Full=Protein FAM154A;
SIMILARITY: Belongs to the FAM154 family.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 37.04 RPKM in Testis
Total median expression: 37.75 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -120.80301-0.401 Picture PostScript Text
3' UTR -61.80402-0.154 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR024963 - STOP/FAM154

Pfam Domains:
PF05217 - STOP protein

ModBase Predicted Comparative 3D Structure on Q8IYX7
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologGenome BrowserNo ortholog
Gene Details     
Gene Sorter     
MGIRGD  WormBase 
Protein SequenceProtein Sequence  Protein Sequence 
AlignmentAlignment  Alignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding
GO:0008017 microtubule binding

Biological Process:
GO:0009631 cold acclimation
GO:0030030 cell projection organization
GO:0045724 positive regulation of cilium assembly
GO:0050821 protein stabilization
GO:0070417 cellular response to cold

Cellular Component:
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005815 microtubule organizing center
GO:0005856 cytoskeleton
GO:0005879 axonemal microtubule
GO:0005929 cilium
GO:0031514 motile cilium
GO:0036064 ciliary basal body
GO:0036126 sperm flagellum
GO:0042995 cell projection


-  Descriptions from all associated GenBank mRNAs
  AK057474 - Homo sapiens cDNA FLJ32912 fis, clone TESTI2006238.
AK292245 - Homo sapiens cDNA FLJ77589 complete cds.
BC033489 - Homo sapiens family with sequence similarity 154, member A, mRNA (cDNA clone MGC:35182 IMAGE:5170510), complete cds.
KJ900327 - Synthetic construct Homo sapiens clone ccsbBroadEn_09721 FAM154A gene, encodes complete protein.
JD144082 - Sequence 125106 from Patent EP1572962.
JD371457 - Sequence 352481 from Patent EP1572962.
JD322112 - Sequence 303136 from Patent EP1572962.
JD423408 - Sequence 404432 from Patent EP1572962.
JD392968 - Sequence 373992 from Patent EP1572962.
JD143942 - Sequence 124966 from Patent EP1572962.
JD494012 - Sequence 475036 from Patent EP1572962.
JD484666 - Sequence 465690 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C9orf138, F154A_HUMAN, FAM154A, NM_153707, Q5VY58, Q8IYX7, uc003zni.1, uc003zni.2, uc003zni.3, uc003zni.4, uc003zni.5
UCSC ID: uc003zni.5
RefSeq Accession: NM_153707
Protein: Q8IYX7 (aka F154A_HUMAN)
CCDS: CCDS6487.1

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.