Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570629)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AKT3 ▸ XIAP ▸ IL1B ▸ FASLG ▸ MAPK3 ▸ BCL6 ▸ DIABLO ▸
IL1A ▸ BCL5 ▸ BCL3 ▸ BCL9 ▸ EPHB2 ▸ IRF6 ▸ MAPK1 ▸
MAPK15 ▸ MAPK9 ▸ MAPK13 ▸ MAPK10 ▸ MAPK11 ▸ MAPK12 ▸ MAPK8 ▸
MAPK7 ▸ MAPK14 ▸ MAPK6 ▸ MAPK4 ▸ IFNG ▸ CASP9 ▸ CASP8 ▸
APAF1 ▸ CASP12 ▸ CASP1 ▸ CASP2 ▸ CAPN1 ▸ DNTT ▸ CAPN10 ▸
CAPN9 ▸ CAPN6 ▸ CAPN13 ▸ CAPN7 ▸ CAPN3 ▸ CAPN15 ▸ IL18 ▸
CAPN12 ▸ CASP6 ▸ CAPN11 ▸ CAPN14 ▸ CAPN8 ▸ CAPN5 ▸ CAPN2 ▸
FADD ▸ CASP4 ▸ CASP7 ▸ CASP10 ▸ CASP5 ▸ CASP16 ▸ CASP14 ▸
ASIP ▸ STS ▸ MCL1 ▸ MMP9 ▸ MMP2 ▸ MMP12 ▸ MMP14 ▸
JUN ▸ MMP11 ▸ MMP3 ▸ MMP10 ▸ MMP25 ▸ MMP20 ▸ CDKN1A ▸
MMP15 ▸ NLRP3 ▸ MMP1 ▸ MMP17 ▸ MMP8 ▸ MMP19 ▸ MMP13 ▸
MMP26 ▸ MMP27 ▸ MMP21 ▸ MMP16 ▸ MMP28 ▸ MMP24 ▸ MMP7 ▸
PDCD11 ▸ PDCD5 ▸ PDCD1 ▸ RNF19A ▸ PDCD7 ▸ PDCD10 ▸ PDCD6 ▸
PDCD2 ▸ PDCD4 ▸ CYCS ▸ CFLAR ▸ NA ▸ IGF1 ▸ PCBD1 ▸
ANXA5 ▸ TGFB1 ▸ AHSA1 ▸ HLA-DRB1 ▸ MPZ ▸ PIK3R1 ▸ INS ▸
PIK3CA ▸ NLRC4 ▸ EPO ▸ PRKCD ▸ VEGFA ▸ MYLIP ▸ PI3 ▸
IL6 ▸ TAT ▸ DDIT3 ▸ PCNA ▸ DFFA ▸ NOS2 ▸ GRAP2 ▸
GSK3B ▸ PRDX2 ▸ TNFRSF1A ▸ NGF ▸ DISC2 ▸ EGF ▸ IL8 ▸
PAK2 ▸ CTSB ▸ DISC1 ▸ SOD1 ▸ BIRC2 ▸ CRK ▸ EIF2AK2 ▸
CAST ▸ IL4 ▸ PTGS2 ▸ CTNNB1 ▸ BID ▸ DFFB ▸ NOS1 ▸
LEP ▸ IRF1 ▸ ROCK1 ▸ FOS ▸ MYC ▸ ABL1 ▸ P2RX7 ▸
SOD2 ▸ DNASE1 ▸ ALPI ▸ HGF ▸ DNASE2 ▸ APP ▸ BDNF ▸
IFNB1 ▸ APEH ▸ CDK2 ▸ MAP3K1 ▸ TCF4 ▸ CTSD ▸ IFI27 ▸
BCR ▸ CAT ▸ IL16 ▸ HTRA2 ▸ TCF21 ▸ TCF19 ▸ RIPK1 ▸
TCF7 ▸ CSF2 ▸ NOS3 ▸ TLR2 ▸ PRKDC ▸ NFKBIA ▸ BIRC7 ▸
BIRC3 ▸ RAC1 ▸ BMP1 ▸ HSPA5 ▸ GAL ▸ HDAC2 ▸ BMP4 ▸
NOD2 ▸ GZMB ▸ TCF20 ▸ NOX1 ▸ IL10 ▸ TCF15 ▸ UPK3B ▸
FGF2 ▸ TCF25 ▸ APOB ▸ TCF12 ▸ TCF23 ▸ TCF24 ▸ TCF3 ▸
SOD3 ▸ MAGT1 ▸ MAP2K1 ▸ ARSK ▸ PPARA ▸ CSF3 ▸ AIM2 ▸
ADCYAP1 ▸ NLRP1 ▸ IL2 ▸ TLR4 ▸ HDAC1 ▸ ATP5O ▸ LMNB1 ▸
CA2 ▸ BAD ▸ NOX4 ▸ TLR3 ▸ STAT1 ▸ ITIH4 ▸ POLDIP2 ▸
HMGB1 ▸ CDC73 ▸ PML ▸ CD8A ▸ PAF1 ▸ SMPD2 ▸ NOX3 ▸
NOX5 ▸ APC ▸ RIPK2 ▸ KRT18 ▸ ENDOG ▸ PRNP ▸ PPP2R2B ▸
WDR61 ▸ TLR7 ▸ BMP5 ▸ IL3 ▸ IL33 ▸ IL7 ▸ IL11 ▸
BMP7 ▸ CTR9 ▸ RB1 ▸ PDLIM7 ▸ BMP15 ▸ HSPB1 ▸ NOD1 ▸
MST1 ▸ PPP2R1A ▸ PPP2CA ▸ STAT3 ▸ TLR5 ▸ BMP10 ▸ IL5 ▸
BMP3 ▸ AGTR1 ▸ RAD51 ▸ HPR ▸ CD79A ▸ SNAP25 ▸ CARD8 ▸
LEO1 ▸ BMP2 ▸ CDK5 ▸ BMP6 ▸ JAK2 ▸ RIPK3 ▸ NPS ▸
HTT ▸ LMNB2 ▸ SMARCD1 ▸ IL20 ▸ SMARCA2 ▸ SMARCD2 ▸ CREB3 ▸
EGFR ▸ CDH1 ▸ TNFRSF1B ▸ CSE ▸ BOC ▸ GSN ▸ PTX3 ▸
LPA ▸ TLR8 ▸ FOXO3 ▸ HIF1A ▸ PTX4 ▸ RBBP7 ▸ ICAM1 ▸
CXCL9 ▸ MAP2K2 ▸ IL21 ▸ ABCC6 ▸ SMARCB1 ▸ TLR10 ▸ SMARCE1 ▸
GP6 ▸ RBBP4 ▸ CCDC88A ▸ WAS ▸ CREB1 ▸ ANXA1 ▸ IGF2 ▸
ARID1A ▸ PLCG1 ▸ TLR1 ▸ GP9 ▸ CREB5 ▸ TRAF6 ▸ SMARCA4 ▸
SMARCC1 ▸ ANGPT1 ▸ ACTL6A ▸ ANGPT2 ▸ GP2 ▸ TXN ▸ IL24 ▸
PGP ▸ SYK ▸ SMARCC2 ▸ BIRC6 ▸ EIF2S1 ▸ MET ▸ CDC6 ▸
GP5 ▸ IL15 ▸ CD4 ▸ IL25 ▸ KDR ▸ MUC20 ▸ PLD1 ▸
PTEN ▸ MUC17 ▸ MUC13 ▸ MUC7 ▸ TOP1 ▸ BECN1 ▸ IL34 ▸
HSPD1 ▸ IKBKB ▸ UCN ▸ SP1 ▸ IL22 ▸ IL27 ▸ TLR9 ▸
CD79B ▸ STX1A ▸ SYT1 ▸ IL37 ▸ RENBP ▸ IL13 ▸ MUC1 ▸
MSC ▸ IL19 ▸ BRCA1 ▸ MEFV ▸ MUC6 ▸ LYN ▸ MUC12 ▸
MUC2 ▸ CDA ▸ ACHE ▸ SMPD1 ▸ CARD9 ▸ PAK1 ▸ MDM2 ▸
MUC15 ▸ MUC21 ▸ HMOX1 ▸ TLR6 ▸ IL26 ▸ CARD11 ▸ MUC22 ▸
CARD6 ▸ RAF1 ▸ PPARG ▸ CCND1 ▸ IL9 ▸ IRF3 ▸ IL31 ▸
RRAS ▸ MUC8 ▸ CDK8 ▸ IL32 ▸ TRAF1 ▸ GATA1 ▸ ROCK2 ▸
MUC19 ▸ PRKCA ▸ MUC4 ▸ MUC16 ▸ PLD2 ▸ PSMD10 ▸ CARD16 ▸
IGF1R ▸ EHMT1 ▸ SLC9A1 ▸ PANX1 ▸ TRAF2 ▸ CUL1 ▸ ATG5 ▸
EPX ▸ PIDD ▸ GUCY2D ▸ CEP112 ▸ HUNK ▸ PRKAR1B ▸ CCL2 ▸
DST ▸ ATF5 ▸ CEP350 ▸ CARD18 ▸ ARSA ▸ SETBP1 ▸ LYPLA1 ▸
HSP90AA1 ▸ PRKAG2 ▸ WNK1 ▸ CEP95 ▸ DES ▸ ME2 ▸ IKBKG ▸
CD47 ▸ SEC14L2 ▸ SKP1 ▸ VIMP ▸ CEP70 ▸ VDAC1 ▸ ALK ▸
MPST ▸ CEP19 ▸ GRB10 ▸ CEP135 ▸ CEP128 ▸ BIRC8 ▸ CEP97 ▸
GRB7 ▸ WNT1 ▸ MAP2K5 ▸ ZGLP1 ▸ NPM1 ▸ RAD17 ▸ CDK4 ▸
CEP44 ▸ RASA1 ▸ CEP290 ▸ ARC ▸ FUT1 ▸ DERL1 ▸ CEP72 ▸
PRKAB1 ▸ E2F1 ▸ PRKAR2B ▸ TNFRSF10A ▸ PRKAB2 ▸ BIRC5 ▸ SLC17A5 ▸
CALM3 ▸ CARD17 ▸ VIM ▸ HIST2H2BE ▸ PTHLH ▸ CEP104 ▸ CCNH ▸
CEP250 ▸ GRB2 ▸ PEA15 ▸ SLCO6A1 ▸ GRB14 ▸ CD40 ▸ CEP68 ▸
PRKCG ▸ PRKAR1A ▸ CTSL ▸ CEP63 ▸ VCP ▸ IRF5 ▸ MAP2K6 ▸
CEP41 ▸ PRKAG1 ▸ CTNND1 ▸ FOXO1 ▸ PSEN1 ▸ PRKAA1 ▸ IRF4 ▸
SOAT1 ▸ CEP192 ▸ ALB ▸ PRKAA2 ▸ GDNF ▸ CCR7 ▸ MIF ▸
NTF3 ▸ PTK2 ▸ ELAVL1 ▸ CEP170 ▸ SUB1 ▸ CEP89 ▸ IRF2 ▸
TIMP3 ▸ SETD2 ▸ CEP78 ▸ CEP152 ▸ PRKACG ▸ PLOD2 ▸ PTBP1 ▸
MAP2K4 ▸ HIP1 ▸ CARD14 ▸ CEP85 ▸ CARD10 ▸ PRKAR2A ▸ CEP120 ▸
CEP57 ▸ CEP76 ▸ CEP164 ▸ MAP2K3 ▸ TCHP ▸ BACE1 ▸ ATF2 ▸
PPP1R3A ▸ BCL2L12 ▸ TRAF3 ▸ CEP55 ▸ H2AFX ▸ MAP2K7 ▸ PNPLA2 ▸
LAT ▸ TARDBP ▸ ADIPOQ ▸ PRKACB ▸ NPY6R ▸ HSF1 ▸ TNFSF12 ▸
ATM ▸ DNAJC5 ▸ STX2 ▸ GSTT1 ▸ PGF ▸ HCLS1 ▸ CDK14 ▸
CDCA5 ▸ PTH ▸ PTCH1 ▸ HIPK2 ▸ GNA11 ▸ ATG3 ▸ NPPA ▸
NOTCH1 ▸ PRG4 ▸ CCR5 ▸ APOE ▸ GPX1 ▸ HTRA3 ▸ TGM2 ▸
BLM ▸ PC ▸ RUNX3 ▸ TRAF7 ▸ NLRP5 ▸ IDO1 ▸ LRP1 ▸
KLF4 ▸ NTF4 ▸ PRG2 ▸ SERP2 ▸ BNIP3 ▸ ERVK-6 ▸ SLPI ▸
CCR3 ▸ IRF8 ▸ NACA ▸ RHO ▸ DYRK1A ▸ TGFB3 ▸ RAD50 ▸
CCR6 ▸ ABCD1 ▸ VIP ▸ CAPNS1 ▸ IFI44 ▸ IL1RN ▸ MED8 ▸
RARA ▸ CSF1 ▸ GYS2 ▸ SHH ▸ CDK20 ▸ TET1 ▸ MTOR ▸
TRAF4 ▸ CENPK ▸ MED4 ▸ LGALS1 ▸ MED12 ▸ GHSR ▸ PAN2 ▸
CDK15 ▸ IFNA2 ▸ NODAL ▸ EDNRA ▸ RBL2 ▸ MAP2 ▸ NLRC5 ▸
PAWR ▸ CTNNBL1 ▸ CDK13 ▸ ETS1 ▸ AFP ▸ CCR10 ▸ FAF1 ▸
PXN ▸ CDK16 ▸ PLK1 ▸ CD2 ▸ HRD ▸ NUP210 ▸ APIP ▸
MME ▸ MT4 ▸ PDGFB ▸ PTPN11 ▸ SEPT4 ▸ MED15 ▸ MED25 ▸
GYS1 ▸ CDK17 ▸ SERPINB9 ▸ ANG ▸ CFL1 ▸ HTRA4 ▸ PLD4 ▸
PLD6 ▸ GPX3 ▸ MED1 ▸ ACR ▸ CDK10 ▸ NUP153 ▸ CXCL13 ▸
TSC22D3 ▸ MICE ▸ NUAK1 ▸ DHCR24 ▸ CDK9 ▸ CDK6 ▸ ACSM3 ▸
MST1R ▸ CHUK ▸ TAC3 ▸ NLRP7 ▸ DAPK2 ▸ MED21 ▸ EIF4G2 ▸
CCK ▸ HDAC4 ▸ CDC42 ▸ EMP2 ▸ C22orf29 ▸ CDK1 ▸ MED7 ▸
COP ▸ SIVA1 ▸ DAXX ▸ CFTR ▸ AIP ▸ TMED7 ▸ WNT3A ▸
IAPP ▸ NUP43 ▸ NUP214 ▸ ETS2 ▸ RAD1 ▸ MED24 ▸ TRAF5 ▸
ANXA6 ▸ MED6 ▸ CCR9 ▸ APOBEC3D ▸ DIDO1 ▸ ANGPT4 ▸ CALB1 ▸
IRF9 ▸ THBS1 ▸ GJA1 ▸ PLD3 ▸ SHC1 ▸ SERPINA1 ▸ SREBF2 ▸
XRCC6 ▸ PIN1 ▸ SMAD7 ▸ SAA1 ▸ BAG3 ▸ S100A12 ▸ SERPINF1 ▸
ACAD8 ▸ ID3 ▸ ITCH ▸ TYR ▸ ING1 ▸ FAM168B ▸ SPP1 ▸
CDK18 ▸ EIF4G1 ▸ EEF1A2 ▸ TET2 ▸ NANOG ▸ IGFBP3 ▸ VDAC3 ▸
E2F3 ▸ CTRL ▸ MAP3K7 ▸ CA8 ▸ PMEL ▸ ADH5 ▸ ANP32A ▸
IFIH1 ▸ HDAC6 ▸ GNRH1 ▸ PAN3 ▸ CDK3 ▸ GRP ▸ SMAD4 ▸
IRF7 ▸ CCR2 ▸ TAC4 ▸ HRK ▸ CDK19 ▸ RAD21 ▸ CPA1 ▸
MTA2 ▸ NUP62 ▸ TFAP2A ▸ UCP2 ▸ PRG3 ▸ EML2 ▸ FKBP4 ▸
MED23 ▸ NR0B1 ▸ QRICH2 ▸ CCNC ▸ ACIN1 ▸ NTN1 ▸ NAIP ▸
SDS ▸ XAF1 ▸ HTRA1 ▸ RAC2 ▸ IRS1 ▸ NAB2 ▸ TNFRSF10B ▸
SREBF1 ▸ TET3 ▸ FHIT ▸ DLG1 ▸ STSP1 ▸ QRICH1 ▸ SMAD3 ▸
KMT2A ▸ DAP3 ▸ CISH ▸ RAD18 ▸ RAC3 ▸ EMP3 ▸ LRRC59 ▸
CIB1 ▸ PLD5 ▸ PPT1 ▸ CPOX ▸ TAC1 ▸ HMGCR ▸ ODC1 ▸
EMP1 ▸ KLKB1 ▸ MTX1 ▸ PAEP ▸ NAB1 ▸ MED13 ▸ VDAC2 ▸
STC1 ▸ CYR61 ▸ MED17 ▸ CD8B ▸ CALR ▸ TRA ▸ BCAP31 ▸
CRYAB ▸ MED14 ▸ JAK1 ▸ GLI1 ▸ CCR1 ▸ PSMB9 ▸ ADM ▸
FLT3 ▸ MT3 ▸ CCR8 ▸ E2F2 ▸ MTA1 ▸ CCR4 ▸ MTA3 ▸
GPI ▸ APEX1 ▸ MED26 ▸ SATB1 ▸ JAK3 ▸ CDK7 ▸ CDK12 ▸
EIF4G3 ▸ NANOS2 ▸ CALML3 ▸ RIPK4 ▸ KLK3 ▸ TNFRSF8 ▸ PARG ▸
IFNA5 ▸ CCL19 ▸ PSENEN ▸ RAD52 ▸ GZMM ▸ SARS2 ▸ NGFR ▸
PPP3CA ▸ GORASP1 ▸ MEF2A ▸ TP73 ▸ PRF1 ▸ PTGES3 ▸ MLH1 ▸
IL1R2 ▸ PICALM ▸ BIRC4 ▸ YWHAG ▸ EIF4B ▸ DSG2 ▸ NR3C1 ▸
ARHGDIA ▸ CAD ▸ HNRNPA0 ▸ PLA2G4A ▸ BCAR1 ▸ SDC2 ▸ PLA2G4B ▸
CDK11A ▸ PSIP1 ▸ MAP4K1 ▸ EIF4A1 ▸ RABEP1 ▸ PIP5K1A ▸ LPAR1 ▸
CDK11B ▸ KARS ▸ NEO1 ▸ CDC2L1 ▸ MDC1 ▸ NUMA1 ▸ SYF2 ▸
AIFM1 ▸ PDE5A ▸ NFATC2 ▸ UNC5B ▸ NVL ▸ NDUFS1 ▸ NUCB2 ▸
FBXW11 ▸ IFT57 ▸ NMT2 ▸ DSG1 ▸ ACVR1C ▸ HEY2 ▸ RBX1 ▸
SAV1 ▸ SOCS5 ▸ LPAR3 ▸ FUK ▸ TRIM28 ▸ AR ▸ CDC2L2 ▸
RNF2 ▸ IL1R1 ▸ UBE4B ▸ BMX ▸ UBC ▸ GMNN ▸ NGFRAP1 ▸
ATG4D ▸ PPARGC1A ▸ DCTN1 ▸ MAPT ▸ GRIPAP1 ▸ CD247 ▸ DSG3 ▸
THAP11 ▸ EIF3S10 ▸ MAP3K14 ▸ COPS6 ▸ AKAP8 ▸ ATN1 ▸ CTTN ▸
HNRNPD ▸ KEAP1 ▸ PLEKHO1 ▸ TNS4 ▸ ACTA1 ▸ HNRNPU ▸ TNFRSF25 ▸
IQGAP1 ▸ NFE2L2 ▸ SCAF11 ▸ PTMA ▸ DBNL ▸ ZBTB16 ▸ ARHGDIB ▸
MAPK8IP3 ▸ PDE10A ▸ GAS2 ▸ ELANE ▸ FUS ▸ EIF3J ▸ WNK3 ▸
YWHAE ▸ STK24 ▸ HRAS ▸
Data information
Please see the Gene Interactions Track Manual.