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IL12B — MIF
Text-mined interactions from Literome
Burger-Kentischer et al., Atherosclerosis 2006
(Aortitis...) :
Importantly, the local aortic expression of ICAM-1, MMP-2, TNF,
IL-12 , and CD40L was
reduced by
MIF blockade, as were the levels of the phospho-c-Jun and C/EBPbeta transcription factors
Cavalcanti et al., PloS one 2011
(Ileitis...) :
Lack of
MIF caused a reduction of TNF-a, IL-12, IFN-? and
IL-23 and an increased expression of IL-22 in ileal mucosa ... Lack of
MIF caused a reduction of TNF-a,
IL-12 , IFN-? and IL-23 and an increased expression of IL-22 in ileal mucosa
Terrazas et al., International journal of biological sciences 2011
:
These findings demonstrate that the
MIF induced early DC maturation and
IL-12 production mediates resistance to T. cruzi infection, probably by activating the p38 pathway