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IL8 — TCF24

Text-mined interactions from Literome

Yamashita et al., Int Arch Allergy Immunol 1999 : In that regard, the transcription factor , nuclear factor, Kappa B ( NF-kappaB ), is an important activator of tumor-necrosis-factor-alpha (TNF-alpha) induced IL-8 gene expression in monocytes, lymphocytes and neutrophils
McDermott et al., Trends Mol Med 2002 (Familial Mediterranean Fever...) : Disorders of interleukin-1 processing and of regulation of nuclear factor kappaB transcription factor , and possibly defective apoptosis, might be involved in the pathogenesis of all but one of these disorders
Varney et al., In Vivo 2002 (Melanoma...) : The differential expression of IL-8 by monocytes following MCP-1 and M-CSF treatments involved activation of the NFkB transcription factor
Yeh et al., J Biol Chem 2004 (Inflammation) : We have shown recently that Ox-PAPC mediated induction of IL-8 transcription is independent of NF-kappaB activation, a major transcription factor utilized by cytokines and lipopolysaccharide for the induction of IL-8 transcription
Méndez-Samperio et al., Mediators Inflamm 2004 (Tuberculosis) : In this study, our experiments were designed to determine the role of the transcription factor nuclear factor-kappaB (NF-kappaB) and intracellular calcium in the production of interleukin (IL)-8 , a main chemotactic factor, by human derived monocytic cell line U937 and by a human epithelial HEp-2 cell line infected with M. bovis BCG
Tamaoki et al., Am J Med 2004 (Chronic Disease...) : Macrolides inhibit the production of many proinflammatory cytokines, such as interleukin (IL)-1, IL-6, IL-8 , and tumor necrosis factor-alpha, perhaps by suppressing the transcription factor nuclear factor-kappaB or activator protein-1
Manna et al., J Biol Chem 2005 : Interleukin-8 induces nuclear transcription factor-kappaB through a TRAF6 dependent pathway
Zhou et al., J Clin Immunol 2004 : IL-8 induction by hyperforin required the activation of AP-1 but not the NF-kappaB transcription factor , thereby distinguishing it from the NF-kappaB dependent IL-8 induction mediated by tumor necrosis factor alpha (TNFalpha)
Day et al., Dig Dis Sci 2004 (Helicobacter Infections) : Interleukin-8 secretion was inhibited following pretreatment of cells with anti-interleukin-18 antibody and by pharmacological inhibition of the nuclear transcription factor , NF-kappaB
Tachado et al., J Leukoc Biol 2007 : In human AM, Pc promoted direct interaction of MR and TLR2, IL-8 release was reduced markedly upon simultaneous blocking of TLR2 and gene silencing of MR, and IL-8 release was dependent in part on transcription factor NF-kappaB and ERK1/2 and JNK MAPKs
Natarajan et al., Microvasc Res 2007 (Inflammation) : Of major importance in the current report was the finding that hypoxia inducible factor-1 (HIF-1), a powerful transcription factor mediating tissue responses to hypoxia, potently regulated hemin induced IL-8 secretion in human MVEC
Erkel et al., Int Immunopharmacol 2007 (Autoimmune Diseases...) : Panepoxydone strongly inhibited hTNF-alpha, IL-8 and NF-kappaB promoter activity in LPS/TPA stimulated MonoMac6 cells with IC ( 50 ) values of 0.5-1 microg/ml by blocking the phosphorylation of IkappaB and subsequent binding of the activated NF-kappaB transcription factor to the DNA
Qiao et al., Neoplasia (New York, N.Y.) 2007 (Neuroblastoma) : Ets1 transcription factor mediates gastrin releasing peptide induced IL-8 regulation in neuroblastoma cells
Vij et al., Am J Respir Cell Mol Biol 2008 (Cystic Fibrosis) : CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells
Lemaire-Ewing et al., Cell Biol Toxicol 2009 (MAP Kinase Signaling System) : Luciferase reporter gene assay using constructs of the human IL-8 gene promoter and Transam assay revealed the involvement of the AP-1 transcription factor in oxysterol dependent IL-8 secretion
Sheikh et al., Hepatology 2008 (Hepatitis C...) : This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8, tumor growth factor beta, and Fas ligand ... This transcription factor plays a key role in the expression of cytokines, tumor necrosis factor alpha (TNF-alpha), interleukin 6, interleukin 8 , tumor growth factor beta, and Fas ligand
Chen et al., Immunity 2008 (Arthritis, Rheumatoid...) : IRF-4 binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
Saraiva et al., Immunity 2009 : Interleukin-10 production by Th1 cells requires interleukin-12 induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
Gerhard et al., Naunyn Schmiedebergs Arch Pharmacol 2011 : Interleukin-8 (IL-8) , transcription factor c-jun and heme oxygenase-1 messenger RNA ( mRNA ) increased more than 2-fold
Rohr-Udilova et al., Hepatology 2012 (Carcinoma, Hepatocellular...) : Activation of the activator protein 1 (AP-1) transcription factor as well as increased serum levels of vascular endothelial growth factor ( VEGF ) and interleukin (IL)-8 predict poor prognosis of patients with hepatocellular carcinomas (HCCs)
Lee et al., Oncol Res 2013 (Adenocarcinoma...) : We investigated the role of HGF induced activation of GRP and Ets-1 transcription factor in expression of the proangiogenic factor IL-8
Sung et al., J Biol Chem 1993 : Stimulation of interleukin-1 gene transcription may be caused by the stimulation of transcription factor activities, including those of AP-1, by these protein phosphatase inhibitors
Wu et al., J Biol Chem 1997 : In contrast to these three positive regulatory elements, the binding of the ubiquitously expressed POU-homeodomain transcription factor , Oct-1, strongly represses transcriptional activity of the IL-8 promoter by binding independently to an element overlapping that of C/EBP