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ARSA — NOX4

Text-mined interactions from Literome

Mitra et al., J Cardiovasc Pharmacol 2012 : Aspirin [acetyl salicylic acid (ASA) ] inhibits nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase and reactive oxygen species generation, a pathway that underlies formation of new capillaries ( angiogenesis ) ... ASA and SA also suppressed NADPH oxidase ( p22, p47, p67, and gp91 messenger RNA ) expression
Wu et al., Oxidative medicine and cellular longevity 2012 (Body Weight...) : In these cardiomyopathic hamsters, chronic ASA treatment (a) completely prevented elevated O ( 2 ) ( - ) production and the NAD ( P ) H oxidase activity, ( b ) significantly slowed down the development of the cardiac hypertrophy and fibrosis