Gene interactions and pathways from curated databases and text-mining

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BLM — CASP1

Text-mined interactions from Literome

Hong et al., Biochem Pharmacol 2003 : Ambroxol ( 10-100 microM ) reduced the 75 mU/mL BLM induced cell death and activation of caspase-3 in macrophages or epithelial cells
Zhao et al., J Toxicol Environ Health 2004 (Inflammation...) : In vitro studies showed that pretreatment of naive AM with a TNF-R2 antibody significantly inhibited BLM induced caspase-3 activity and apoptosis
FlaquƩ et al., Environ Mol Mutagen 2006 (Chromosome Aberrations) : BLM induced ICE , dicentrics, and interstitial acentric fragments in CHE cells, but only ICE in CPC cells ... Almost 100 % of the BLM induced ICE in both cell lines consisted of pairs formed by an incomplete chromosome and a terminal fragment ... Moreover, the present study shows that an increase in the chromosome number does not necessarily result in an increase in the frequency of BLM induced ICE