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BLM — CASP1
Text-mined interactions from Literome
Hong et al., Biochem Pharmacol 2003
:
Ambroxol ( 10-100 microM ) reduced the 75 mU/mL
BLM induced cell death and activation of
caspase-3 in macrophages or epithelial cells
Zhao et al., J Toxicol Environ Health 2004
(Inflammation...) :
In vitro studies showed that pretreatment of naive AM with a TNF-R2 antibody significantly inhibited
BLM induced
caspase-3 activity and apoptosis
FlaquƩ et al., Environ Mol Mutagen 2006
(Chromosome Aberrations) :
BLM induced
ICE , dicentrics, and interstitial acentric fragments in CHE cells, but only ICE in CPC cells ... Almost 100 % of the
BLM induced
ICE in both cell lines consisted of pairs formed by an incomplete chromosome and a terminal fragment ... Moreover, the present study shows that an increase in the chromosome number does not necessarily result in an increase in the frequency of
BLM induced
ICE