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PRKG2 — REN

Text-mined interactions from Literome

Hofmann et al., Methods Mol Biol 2013 : cGKI relaxes smooth muscle tone and prevents platelet aggregation, whereas cGKII inhibits renin secretion, chloride/water secretion in the small intestine, the resetting of the clock during early night, and endochondral bone growth
Gambaryan et al., J Clin Invest 1996 (Dehydration) : Whereas additional data suggest that cGK I may primarily mediate cGMP related changes in renal hemodynamics, cGK II may regulate renin release and ATL ion transport
Gambaryan et al., Proc Natl Acad Sci U S A 1998 : Expression of either cGK II or cGK I in JG cells by using adenoviral vectors enhanced the inhibition of forskolin stimulated renin release by 8-pCPT-cGMP to 50 % ... Our results indicate that cGK II , and possibly cGK I, can mediate cGMP inhibitory effects on renin release and are physiological components of the cGMP signal transduction system which opposes the RAAS