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CD44 — MYLIP

Text-mined interactions from Literome

Wang et al., PloS one 2008 : MicroRNA miR-328 regulates zonation morphogenesis by targeting CD44 expression ... Protein analysis indicated that miR-328 repressed CD44 expression
Bourguignon et al., J Biol Chem 2012 (Carcinoma, Squamous Cell...) : Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma ... Further analysis reveals that microRNA-302 (miR-302) is controlled by an upstream promoter containing Oct4-Sox2-Nanog binding sites, whereas chromatin immunoprecipitation ( ChIP ) assays demonstrate that stimulation of miR-302 expression by HA-CD44 is Oct4-Sox2-Nanog dependent in HNSCC-specific CSCs ... Taken together, these findings strongly support the contention that the HA-induced CD44v3 interaction with Oct4-Sox2-Nanog signaling plays a pivotal role in miR-302 production leading to AOF1/AOF2/DNMT1 down-regulation and survival of protein activation