Gene interactions and pathways from curated databases and text-mining

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IL6 — PDLIM7

Text-mined interactions from Literome

Eliopoulos et al., J Biol Chem 1999 : In addition, we have found that p38 inhibition significantly impaired LMP1 mediated interleukin-6 and -8 expression
Dawson et al., Virology 2000 (Nasopharyngeal Neoplasms) : Although B95.8-LMP1 induced growth inhibition, expression of certain cell surface molecules ( CD40, CD44, and CD54 ), and secretion of interleukin-6 and -8 in SCC12F cells, stable CAO-LMP1 expression failed to elicit these effects
Chen et al., J Virol 2003 : This in turn would establish a positive feedback loop of IL-6 induced STAT activation, LMP1 and Qp-EBNA1 expression, and viral genome persistence
Buettner et al., Virchows Arch 2006 (Nasopharyngeal Neoplasms) : It was proposed recently that LMP1 expression in epithelial cells may be regulated through a loop involving activated signal transducer and activator of transcription 3 ( STAT3 ), LMP1, LMP1 mediated induction of interleukin (IL)-6 expression and STAT3 activation through the IL-6 receptor
Kung et al., J Virol 2008 : LMP1-CTAR1 constitutively activates STAT3, and this activation was not due to the induction of interleukin 6 (IL-6)
Ikeda et al., Mol Cell Biol 2008 : In the present study, we found that ectopic expression of STAP-2 inhibited Epstein-Barr virus ( EBV ) LMP1 mediated NF-kappaB signaling and interleukin-6 expression
Lin et al., Cytokine 2010 : Here we have identified an important signaling event mediated by a dsRNA dependent serine/threonine protein kinase, PKR, in regulating LMP1 induced IL-6 and IL-10 expression
Arcipowski et al., PloS one 2012 : We determined that TAK1 was required for JNK activation and interleukin-6 (IL-6) production mediated by CD40 and LMP1 , in both mouse and human B cells