Gene interactions and pathways from curated databases and text-mining

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CD40LG — SYT1

Text-mined interactions from Literome

Schaffer et al., J Immunol 1999 : Electrophoretic mobility shift assays showed that p50/p65/c-Rel and STAT-6 are effectively induced by CD40L and IL-4, respectively, and bind to specific DNA motifs within the ECS
Zhang et al., Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2004 (Burkitt Lymphoma) : While CD154 induced phosphorylation of p65 , phosphorylation and degradation of IkappaB-alpha, and nuclear translocation of p50, p65, and c-Rel were all blocked by BAY11-7082 ; Lactacystein only inhibited degradation of IkappaB-alpha and p65 nuclear translocation