Hill et al., Biochem Biophys Res Commun 2010
:
IFNgamma mediates DUOX2 expression via a STAT independent signaling pathway ... Given the known role of DUOX for host defense in the gut and respiratory tract, we characterized potential mechanisms that control DUOX2 expression in response to interferon gamma (IFNgamma) in respiratory tract epithelium ... We discovered that IFNgamma mediated DUOX2 expression was regulated by a STAT independent, JAK independent pathway
Wu et al., J Biol Chem 2011
:
Up-regulation and sustained activation of Stat1 are essential for interferon-gamma (IFN-gamma) induced dual oxidase 2 (Duox2) and dual oxidase A2 (DuoxA2) expression in human pancreatic cancer cell lines