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AKT1S1 — RPS6KB1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: RPS6KB1 → AKT1S1 (decreases, AKT1S1 Activity) Sancak et al., Mol Cell 2007
  Evidence: PRAS40 inhibits cell growth, S6K1 phosphorylation, and rheb-induced activation of the mTORC1 pathway, and in vitro it prevents the great increase in mTORC1 kinase activity induced by rheb1-GTP.

Text-mined interactions from Literome

Akcakanat et al., Biochem Biophys Res Commun 2007 : mTORC1 is rapamycin-sensitive, and results in phosphorylation of 4E-BP1 and S6K1
Dibble et al., Mol Cell Biol 2009 : We find that Rictor-T1135 is directly phosphorylated by the mTORC1 dependent kinase S6K1
Magnuson et al., Biochem J 2012 : mTORC1 ( mammalian TORC1 ) phosphorylates and activates S6K1 and S6K2, whose first identified substrate was rpS6 ( ribosomal protein S6 ), a component of the 40S ribosome