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IL1A — NPS
Text-mined interactions from Literome
Hulkower et al., Agents Actions 1991
:
Although
IL-1 induced the
NPs and PGE2, it did so without detectable translocation of PKC
Yaraee et al., Iran J Allergy Asthma Immunol 2003
:
Each neuropeptide separately has upregulated IL-1 beta production by HSV- 1 infected macrophages with the greatest effect at the concentrations of 1 09M for both SP and CGRP, but no synergistic effect on
IL-1 production has been observed in the
presence of both
neuropeptides at optimal concentrations
Shi et al., Anesth Analg 2011
(Pain) :
We then investigated whether these
neuropeptides could
stimulate production of
IL-1ß in a keratinocyte cell line ( REKs ), and could increase the expression of inflammasome component proteins including NALP1 and caspase-1
Segat et al., Nanomedicine (Lond) 2011
:
Bare
ORMOSIL-NPs effectively
stimulated the production of
IL-1ß/IL-6/TNF-a/IL-8 by monocytes and of IL-8 by polymorphonuclear leukocytes ( PMNs )
Xue et al., Toxicol Lett 2012
(Inflammation...) :
In addition, the secretion levels of TNF-a,
IL-1ß and IL-6 were variably
increased by all four
NPs
Ferin et al., Ann N Y Acad Sci 1993
:
In conclusion, we have demonstrated that in the primate increased activity of the immune system and the consequent
IL-1 release
result in the activation of
neuropeptides of the adrenal axis, mainly CRF and AVP