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BCL10 — GRAP2
Text-mined interactions from Literome
Lakics et al., J Immunol 2000
:
More strikingly, LPS induced phosphorylation of
p38 mitogen activated protein kinase and c-Jun N-terminal kinase was strongly
repressed by
Bcl-xL overexpression, offering a possible mechanism for the inhibition of LPS induced cytokine production
Bodero et al., Biochem Biophys Res Commun 2003
(MAP Kinase Signaling System) :
UV-induced phosphorylation of Bcl10 was inhibited by the p38 stress activated protein kinase inhibitors SB203580 and PD169316, suggesting that
p38 is
required for UV-mediated phosphorylation of
Bcl10
Wang et al., Chin J Physiol 2007
:
Scutellarin decreased caspase-3 activity, increased
Bcl-XL expression,
inhibited p38 phosphorylation and attenuated ROS production
Chen et al., Toxicology 2009
(Neuroblastoma) :
SB202190 (
p38 MAPK inhibitor ) and SP600125 ( JNK inhibitor )
attenuated mitochondrial depolarization, degradation of
Bcl-2/Bcl-xL , and mitochondrial translocation of Bax
Harnett et al., Cell Biochem Funct 2013
:
Interestingly,
Bcl-xL expression
inhibited p38 activation, but Z-VAD-fmk treatment did not, indicating that activation of this MAPK occurs downstream of mitochondrial dysfunction and is independent of caspases