Gene interactions and pathways from curated databases and text-mining

◀ Back to BMP2

BMP2 — CREB3

Text-mined interactions from Literome

Zhang et al., PloS one 2011 : Importantly, we found that the PTH-CREB signaling pathway functioned as an effective activator of BMP2 expression, as pharmacologic and genetic modulation of PTH-CREB activity significantly affected BMP2 expression levels in these cells
Lee et al., J Cell Physiol 1997 : We showed the following points : 1 ) in micromass cultures, activation of PKA enhances chondrogenesis and increases the phosphorylation of CREB; 2 ) BMP-2 , a chondrogenic stimulator, increases PKA activity and the level of phosphorylated CREB ( P-CREB ) ; 3 ) H8, a PKA inhibitor, inhibits chondrogenesis ; 4 ) the chondrogenic activities of BMP-2 and cAMP are suppressed by H8 ; and 5 ) long-term TPA treatment ( a protein kinase C ( PKC ) modulator ) inhibits chondrogenesis and decreases the levels of CREB and P-CREB