Kim et al., Biochem Biophys Res Commun 2005
:
Taken together, these results suggest that hypoxic condition attenuates adipocyte differentiation by inhibition of PPARgamma expression in a HDAC independent manner and by activation of AMPK which impairs clonal expansion phase
Turturro et al., Am J Physiol Cell Physiol 2007
:
These results are consistent with three pathways through which glitazones may act in effecting metabolic processes ( ammoniagenesis and gluconeogenesis ) as well as cellular growth : 1 ) PPAR-gamma dependent and PPAR-gamma independent pathways, 2 ) P-ERK activation, and 3 ) mitochondrial AMPK activation
Tong et al., J Anim Sci 2008
:
Inhibition of AMPK by compound C enhanced the expression of PPARgamma Guo et al., Acta Pharmacol Sin 2010
(Insulinoma) :
AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARalpha, but not PPARgamma , in rat insulinoma cell line INS-1